UniProt Accession

 D3YWM6_MOUSE; D3YWM6 

Genbank Protein ID

 AC166833 

Genbank Nucleotide ID

  

Protein Name

 Uncharacterized protein 

Protein Synonyms/Alias

  

Gene Name

 Ces2d-ps 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
539	GRLQFWTKTLPQKIQ	acetylation	[1, 2]
539	GRLQFWTKTLPQKIQ	succinylation	[1]
549	PQKIQELKASQDKHR	acetylation	[3]

Reference

 [1] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [2] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654]
 [3] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Hydrolase; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 558 AA 

Protein Sequence

Gene Ontology

 GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW. 

Interpro

 IPR002018; CarbesteraseB.
 IPR019826; Carboxylesterase_B_AS.
 IPR019819; Carboxylesterase_B_CS. 

Pfam

 PF00135; COesterase 

SMART

  

PROSITE

 PS00122; CARBOXYLESTERASE_B_1
 PS00941; CARBOXYLESTERASE_B_2 

PRINTS