CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-021277
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Oxysterol-binding protein-related protein 2 
Protein Synonyms/Alias
 ORP-2; OSBP-related protein 2 
Gene Name
 OSBPL2 
Gene Synonyms/Alias
 KIAA0772; ORP2 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
138SQWERTGKPFNPLLGubiquitination[1]
197PKLKFWGKSVEAEPRubiquitination[1]
349VQVIPGSKLLWRINTubiquitination[1]
411MDLASQEKERLEEKQubiquitination[1]
Reference
 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 
Functional Description
 Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3- phosphate. 
Sequence Annotation
  
Keyword
 Alternative splicing; Complete proteome; Lipid transport; Lipid-binding; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 480 AA 
Protein Sequence
MNGEEEFFDA VTEANQKVTG MIDLDTSKNN RIGKTGERPS QENGIQKHRT SLPAPMFSRS 60
DFSVWTILKK CVGLELSKIT MPIAFNEPLS FLQRITEYME HVYLIHRASC QPQPLERMQS 120
VAAFAVSAVA SQWERTGKPF NPLLGETYEL IREDLGFRFI SEQVSHHPPI SAFHSEGLNH 180
DFLFHGSIYP KLKFWGKSVE AEPRGTITLE LLKHNEAYTW TNPTCCVHNV IIGKLWIEQY 240
GTVEILNHRT GHKCVLHFKP CGLFGKELHK VEGHIQDKNK KKLFMIYGKW TECLWGIDPV 300
SYESFKKQER RGDHLRKAKL DEDSGKADSD VADDVPVAQE TVQVIPGSKL LWRINTRPPN 360
SAQMYNFTSF TVSLNELETG MEKTLPPTDC RLRPDIRGME NGNMDLASQE KERLEEKQRE 420
ARRERAKEEA EWQTRWFYPG NNPYTGTPDW LYAGDYFERN FSDCPDIY 468 
Gene Ontology
 GO:0015485; F:cholesterol binding; IDA:BHF-UCL.
 GO:0006869; P:lipid transport; IEA:UniProtKB-KW. 
Interpro
 IPR000648; Oxysterol-bd.
 IPR018494; Oxysterol-bd_CS. 
Pfam
 PF01237; Oxysterol_BP 
SMART
  
PROSITE
 PS01013; OSBP 
PRINTS