CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017396
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc finger CCHC domain-containing protein 7 
Protein Synonyms/Alias
  
Gene Name
 ZCCHC7 
Gene Synonyms/Alias
 HSPC086 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
131QSNELVDKKCKSDIEubiquitination[1]
132SNELVDKKCKSDIEKubiquitination[2]
239QRYYSANKNIICRNCubiquitination[2]
384FICYYDDKYEIQEREubiquitination[2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
 ZN_FING 241 258 CCHC-type 1.
 ZN_FING 263 280 CCHC-type 2.
 ZN_FING 304 321 CCHC-type 3.
 ZN_FING 348 365 CCHC-type 4.
 MOD_RES 482 482 Phosphoserine.  
Keyword
 Alternative splicing; Complete proteome; Metal-binding; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 543 AA 
Protein Sequence
MMFGGYETIE AYEDDLYRDE SSSELSVDSE VEFQLYSQIH YAQDLDDVIR EEEHEEKNSG 60
NSESSSSKPN QKKLIVLSDS EVIQLSDGSE VITLSDEDSI YRCKGKNVRV QAQENAHGLS 120
SSLQSNELVD KKCKSDIEKP KSEERSGVIR EVMIIEVSSS EEEESTISEG DNVESWMLLG 180
CEVDDKDDDI LLNLVGCENS VTEGEDGINW SISDKDIEAQ IANNRTPGRW TQRYYSANKN 240
IICRNCDKRG HLSKNCPLPR KVRRCFLCSR RGHLLYSCPA PLCEYCPVPK MLDHSCLFRH 300
SWDKQCDRCH MLGHYTDACT EIWRQYHLTT KPGPPKKPKT PSRPSALAYC YHCAQKGHYG 360
HECPEREVYD PSPVSPFICY YDDKYEIQER EKRLKQKIKV LKKNGVIPEP SKLPYIKAAN 420
ENPHHDIRKG RASWKSNRWP QENKETQKEM KNKNRNWEKH RKADRHREVD EDFPRGPKTY 480
SSPGSFKTQK PSKPFHRSSH YHTSREDKSP KEGKRGKQKK KERCWEDDDN DNLFLIKQRK 540
KKS 543 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0005730; C:nucleolus; IDA:HPA.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR001878; Znf_CCHC. 
Pfam
 PF00098; zf-CCHC 
SMART
 SM00343; ZnF_C2HC 
PROSITE
 PS50158; ZF_CCHC 
PRINTS