UniProt Accession

 SUSD1_HUMAN; Q6UWL2; A1A4C5; A8KA03; Q5T8V6; Q5T8V7; Q6P9G7; Q8WU83; Q96DM9; Q9H6V2; Q9NTA7 

Genbank Protein ID

 AY358746; AK025486; AK056704; AK292868; AL158824; AL138756; AL158824; AL138756; AL138756; AL158824; AL138756; AL158824; CH471105; BC021125; BC052314; BC060770; AL137432 

Genbank Nucleotide ID

 AAQ89106.1; BAB15149.1; BAB71259.1; BAF85557.1; CAI12347.2; CAI12347.2; CAI12348.2; CAI12348.2; CAI95299.2; CAI95299.2; CAI95300.2; CAI95300.2; EAW59093.1; AAH21125.1; AAH52314.1; AAH60770.2; CAB70735.1 

Protein Name

 Sushi domain-containing protein 1 

Protein Synonyms/Alias

  

Gene Name

 SUSD1 

Gene Synonyms/Alias

 UNQ2438/PRO4999 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
686	EYYNAPLKRGSDYCI	ubiquitination	[1, 2]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

  

Sequence Annotation

 DOMAIN 35 72 EGF-like 1.
 DOMAIN 73 112 EGF-like 2; calcium-binding (Potential).
 DOMAIN 125 162 EGF-like 3; calcium-binding (Potential).
 DOMAIN 177 236 Sushi 1.
 DOMAIN 237 296 Sushi 2.
 CARBOHYD 87 87 N-linked (GlcNAc...) (Potential).
 CARBOHYD 112 112 N-linked (GlcNAc...) (Potential).
 CARBOHYD 193 193 N-linked (GlcNAc...) (Potential).
 CARBOHYD 253 253 N-linked (GlcNAc...).
 CARBOHYD 348 348 N-linked (GlcNAc...) (Potential).
 CARBOHYD 367 367 N-linked (GlcNAc...) (Potential).
 CARBOHYD 563 563 N-linked (GlcNAc...) (Potential).
 DISULFID 39 48 By similarity.
 DISULFID 42 57 By similarity.
 DISULFID 59 71 By similarity.
 DISULFID 77 91 By similarity.
 DISULFID 85 100 By similarity.
 DISULFID 129 141 By similarity.
 DISULFID 135 150 By similarity.
 DISULFID 179 221 By similarity.
 DISULFID 206 234 By similarity.
 DISULFID 239 281 By similarity.
 DISULFID 266 294 By similarity.  

Keyword

 Alternative splicing; Calcium; Complete proteome; Disulfide bond; EGF-like domain; Glycoprotein; Membrane; Polymorphism; Reference proteome; Repeat; Signal; Sushi; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 747 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005509; F:calcium ion binding; IEA:InterPro. 

Interpro

 IPR000742; EG-like_dom.
 IPR001881; EGF-like_Ca-bd.
 IPR013032; EGF-like_CS.
 IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
 IPR018097; EGF_Ca-bd_CS.
 IPR023413; GFP_like.
 IPR000436; Sushi_SCR_CCP. 

Pfam

 PF07645; EGF_CA
 PF00084; Sushi 

SMART

 SM00032; CCP
 SM00181; EGF
 SM00179; EGF_CA 

PROSITE

 PS00010; ASX_HYDROXYL
 PS00022; EGF_1
 PS01186; EGF_2
 PS50026; EGF_3
 PS01187; EGF_CA
 PS50923; SUSHI 

PRINTS