| Tag | Content |
|---|
| CPLM ID | CPLM-003610 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Thioredoxin-2 |
Protein Synonyms/Alias | Trx-2; Protein-disulfide reductase |
Gene Name | trxC |
Gene Synonyms/Alias | yfiG; b2582; JW2566 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 89 | SGKVRFVKVNTEAER | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | Efficient electron donor for the essential enzyme ribonucleotide reductase. Is also able to reduce the interchain disulfide bridges of insulin. |
Sequence Annotation | DOMAIN 26 139 Thioredoxin.
ZN_FING 5 18 Potential.
DISULFID 64 67 Redox-active (By similarity). |
Keyword | Complete proteome; Cytoplasm; Disulfide bond; Electron transport; Metal-binding; NAD; Oxidoreductase; Redox-active center; Reference proteome; Transport; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 139 AA |
Protein Sequence | MNTVCTHCQA INRIPDDRIE DAAKCGRCGH DLFDGEVINA TGETLDKLLK DDLPVVIDFW 60
APWCGPCRNF APIFEDVAQE RSGKVRFVKV NTEAERELSS RFGIRSIPTI MIFKNGQVVD 120
MLNGAVPKAP FDSWLNESL 139 |
Gene Ontology | GO:0005737; C:cytoplasm; IMP:EcoCyc. GO:0009055; F:electron carrier activity; IEA:InterPro. GO:0015035; F:protein disulfide oxidoreductase activity; IMP:EcoCyc. GO:0047134; F:protein-disulfide reductase activity; IEA:EC. GO:0008270; F:zinc ion binding; IDA:EcoCyc. GO:0045454; P:cell redox homeostasis; IEA:InterPro. GO:0022900; P:electron transport chain; IEA:UniProtKB-KW. GO:0006662; P:glycerol ether metabolic process; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |