UniProt Accession

 RAN_DROME; Q9VZ23; Q9NH14; Q9NHN9 

Genbank Protein ID

 AF233584; AF220950; AE014298; AY061398; AY070533; BT003574; AF233585 

Genbank Nucleotide ID

 AAF60289.1; AAF30287.1; AAF48008.1; AAL28946.1; AAL48004.1; AAO39578.1; AAF60290.1 

Protein Name

 GTP-binding nuclear protein Ran 

Protein Synonyms/Alias

 Ras-related nuclear protein 

Gene Name

 ran 

Gene Synonyms/Alias

 Ran10A; CG1404 

Created Date

 July 27, 2013 

Organism

 Drosophila melanogaster (Fruit fly) 

NCBI Taxa ID

 7227 

Lysine Modification

Position	Peptide	Type	References
71	WDTAGQEKFGGLRDG	acetylation	[1]
99	VTSRVTYKNVPNWHR	acetylation	[1]
191	PPEVKMDKDWQAQIE	acetylation	[1]

Reference

 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 

Functional Description

 GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. RanGTP modulates both spindle and nuclear envelope assembly supporting a mitotic role of Ran. 

Sequence Annotation

 NP_BIND 17 24 GTP (By similarity).
 NP_BIND 65 69 GTP (By similarity).
 NP_BIND 122 125 GTP (By similarity).  

Keyword

 Cell cycle; Cell division; Complete proteome; Cytoplasm; Cytoskeleton; GTP-binding; Mitosis; Nucleotide-binding; Nucleus; Protein transport; Reference proteome; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 216 AA 

Protein Sequence

Gene Ontology

 GO:0005811; C:lipid particle; IDA:FlyBase.
 GO:0005875; C:microtubule associated complex; IDA:FlyBase.
 GO:0072686; C:mitotic spindle; IDA:FlyBase.
 GO:0005880; C:nuclear microtubule; IDA:UniProtKB.
 GO:0005525; F:GTP binding; IDA:UniProtKB.
 GO:0003924; F:GTPase activity; ISS:FlyBase.
 GO:0007015; P:actin filament organization; IMP:FlyBase.
 GO:0007155; P:cell adhesion; IMP:FlyBase.
 GO:0051301; P:cell division; IEA:UniProtKB-KW.
 GO:0006886; P:intracellular protein transport; TAS:UniProtKB.
 GO:0000212; P:meiotic spindle organization; IMP:FlyBase.
 GO:0007067; P:mitosis; IEA:UniProtKB-KW.
 GO:0048812; P:neuron projection morphogenesis; IMP:FlyBase.
 GO:0006913; P:nucleocytoplasmic transport; IEA:InterPro.
 GO:0008360; P:regulation of cell shape; IMP:FlyBase.
 GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. 

Interpro

 IPR027417; P-loop_NTPase.
 IPR002041; Ran_GTPase.
 IPR005225; Small_GTP-bd_dom.
 IPR001806; Small_GTPase. 

Pfam

 PF00071; Ras 

SMART

 SM00176; RAN 

PROSITE

 PS51418; RAN 

PRINTS

 PR00627; GTPRANTC4.