| Tag | Content |
|---|
| CPLM ID | CPLM-019992 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Ubiquilin-4 |
Protein Synonyms/Alias | Ataxin-1 interacting ubiquitin-like protein; A1Up; Ataxin-1 ubiquitin-like-interacting protein A1U; Connexin43-interacting protein of 75 kDa; CIP75 |
Gene Name | Ubqln4 |
Gene Synonyms/Alias | Cip75; Ubin |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 46 | EEISRRFKAQQDQLV | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Plays a role in the regulation of proteasomal protein degradation. Depending on the case, may promote or inhibit proteasomal protein degradation. |
Sequence Annotation | DOMAIN 13 87 Ubiquitin-like.
DOMAIN 548 593 UBA. |
Keyword | 3D-structure; Complete proteome; Cytoplasm; Endoplasmic reticulum; Nucleus; Reference proteome; Ubl conjugation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 596 AA |
Protein Sequence | MAEPSGAETR PQIRVTVKTP KDKEEIVICD QASVKEFKEE ISRRFKAQQD QLVLIFAGKI 60
LKDGDTLSQH GIKDGLTVHL VIKTPQKAQD PVTAAASPPS TPDSASAPST TPASPAAAPV 120
QPCSSGNTTS DAGSGGGPSP VAAEGPSSAT ASILSGFGGI LGLGSLGLGS ANFMELQQQM 180
QRQLMSNPEM LSQIMENPLV QDMMSNPDLM RHMIMANPQM QQLMERNPEI SHMLNNPELM 240
RQTMELARNP AMMQEMMRNQ DRALSNLESV PGGYNALRRM YTDIQEPMFT AAREQFGNNP 300
FSSLAGNSDN SSSQPLRTEN REPLPNPWSP SPPTSQAPGS GGEGTGGSGT SQVHPTVSNP 360
FGINAASLGS GMFNSPEMQA LLQQISENPQ LMQNVISAPY MRTMMQTLAQ NPDFAAQMMV 420
NVPLFAGNPQ LQEQLRLQLP VFLQQMQNPE SLSILTNPRA MQALLQIQQG LQTLQTEAPG 480
LVPSLGSFGT PRTSVPLAGS NSGSSAEAPT SSPGVPATSP PSAGSNAQQQ LMQQMIQLLS 540
GSGNSQVPMP EVRFQQQLEQ LNSMGFINRE ANLQALIATG GDINAAIERL LGSQLS 596 |
Gene Ontology | GO:0005829; C:cytosol; IDA:MGI. GO:0031597; C:cytosolic proteasome complex; IEA:Compara. GO:0005789; C:endoplasmic reticulum membrane; IDA:MGI. GO:0031595; C:nuclear proteasome complex; IEA:Compara. GO:0005634; C:nucleus; ISS:UniProtKB. GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. GO:0031593; F:polyubiquitin binding; ISS:UniProtKB. GO:0032434; P:regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |