CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-018618
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Beta-synuclein 
Protein Synonyms/Alias
  
Gene Name
 Sncb 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
12MKGLSMAKEGVVAAAubiquitination[1]
57GVASVAEKTKEQASHubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 May be involved in neuronal plasticity (By similarity). 
Sequence Annotation
 REPEAT 20 30 1.
 REPEAT 31 41 2.
 REPEAT 42 55 3; approximate.
 REPEAT 56 66 4.
 REGION 20 66 4 X 11 AA tandem repeats of [EGS]-K-T-K-
 MOD_RES 117 117 Phosphoserine; by BARK1, CK2 and GRK5 (By  
Keyword
 Complete proteome; Cytoplasm; Direct protein sequencing; Phosphoprotein; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 133 AA 
Protein Sequence
MDVFMKGLSM AKEGVVAAAE KTKQGVTEAA EKTKEGVLYV GSKTSGVVQG VASVAEKTKE 60
QASHLGGAVF SGAGNIAAAT GLVKKEEFPT DLKPEEVAQE AAEEPLIEPL MEPEGESYED 120
SPQEEYQEYE PEA 133 
Gene Ontology
 GO:0005794; C:Golgi apparatus; IEA:Compara.
 GO:0030426; C:growth cone; IEA:Compara.
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0043025; C:neuronal cell body; IEA:Compara.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0045202; C:synapse; IDA:MGI.
 GO:0043195; C:terminal bouton; IEA:Compara.
 GO:0005509; F:calcium ion binding; IEA:Compara.
 GO:0042417; P:dopamine metabolic process; IGI:MGI.
 GO:0043524; P:negative regulation of neuron apoptotic process; IGI:MGI.
 GO:0050808; P:synapse organization; IGI:MGI.
 GO:0007268; P:synaptic transmission; IGI:MGI. 
Interpro
 IPR001058; Synuclein.
 IPR002461; Synuclein_beta. 
Pfam
 PF01387; Synuclein 
SMART
  
PROSITE
  
PRINTS
 PR01213; BSYNUCLEIN.
 PR01211; SYNUCLEIN.