CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042042
UniProt Accession
Genbank Protein ID
 U47924 
Genbank Nucleotide ID
  
Protein Name
 Prolyl 3-hydroxylase 3 
Protein Synonyms/Alias
  
Gene Name
 LEPREL2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
516FEGLTVLKAAQLARAubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 735 AA 
Protein Sequence
MLRLLRPLLL LLLLPPPGSP EPPGLTQLSP GAPPQAPDLL YADGLRAYAA GAWAPAVALL 60
REALRSQAAL GRVRLDCGAS CAADPGAALP AVLLGAPEPD SGPGPTQGSW ERQLLRAALR 120
RADCLTQCAA RRLGPGGAAR RVGSALRDAF RRREPYNYLQ RAYYQLKKLD LAAAAAHTFF 180
VANPMHLQMR EDMAKYRRMS GVRPQSFRDL ETPPHWAAYD TGLELLGRQE AGLALPRLEE 240
ALQGSLAQME SCRADCEGPE EQQGAEEEED GAASQGGLYE AIAGHWIQVL QCRQRCVGET 300
ATRPGRSFPV PDFLPNQLRR LHEAHAQVGN LSQAIENVLS VLLFYPEDEA AKRALNQYQA 360
QLGEPRPGLG PREDIQRFIL RSLGEKRQLY YAMEHLGTSF KDPDPWTPAA LIPEALREKL 420
REDQEKRPWD HEPVKPKPLT YWKDVLLLEG VTLTQDSRQL NGSERAVLDG LLTPAECGVL 480
LQLAKDAAGA GARSGYRGRR SPHTPHERFE GLTVLKAAQL ARAGTVGSQG AKLLLEVSER 540
VRTLTQAYFS PERPLHLSFT HLVCRSAIEG EQEQRMDLSH PVHADNCVLD PDTGECWREP 600
PAYTYRDYSG LLYLNDDFQG GDLFFTEPNA LTVTARVRPR CGRLVAFSSG VENPHGVWAV 660
TRGRRCALAL WHTWAPEHRE QEWIEAKELL QESQEEEEEE EEEMPSKDPS PEPPSRRHQR 720
VQDKTGRAPR VREEL 735 
Gene Ontology
 GO:0005506; F:iron ion binding; IEA:InterPro.
 GO:0031418; F:L-ascorbic acid binding; IEA:InterPro.
 GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro. 
Interpro
 IPR005123; Oxoglu/Fe-dep_dioxygenase.
 IPR006620; Pro_4_hyd_alph.
 IPR011990; TPR-like_helical. 
Pfam
 PF13640; 2OG-FeII_Oxy_3 
SMART
 SM00702; P4Hc 
PROSITE
 PS51471; FE2OG_OXY 
PRINTS