CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042735
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein scribble homolog 
Protein Synonyms/Alias
  
Gene Name
 SCRIB 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
101LRELCIQKAPGERLGubiquitination[1]
134DEGIFISKVSPTGAAubiquitination[2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 650 AA 
Protein Sequence
XRLPRAGGPL GLSIVGGSDH SSHPFGVQEP GVFISKVLPR GLAARSGLRV GDRILAVNGQ 60
DVRDATHQEA VSALLRPCLE LSLLVRRDPA PPGLRELCIQ KAPGERLGIS IRGGARGHAG 120
NPRDPTDEGI FISKVSPTGA AGRDGRLRVG LRLLEVNQQS LLGLTHGEAV QLLRSVGDTL 180
TVLVCDGFEA STDAALEVSP GVIANPFAAG IGHRNSLESI SSIDRELSPE GPGKEKELPG 240
QTLHWGPEAT EAAGRGLQPL KLDYRALAAV PSAGSVQRVP SGAAGGKMAE SPCSPSGQQP 300
PSPPSPDELP ANVKQAYRAF AAVPTSHPPE DAPAQPPTPG PAASPEQLSF RERQKYFELE 360
VRVPQAEGPP KRVSLVGADD LRKMQEEEGE GHGSGVGVGS RLVWPDPPCP PAARKLQQKR 420
AQMLREAAEA GAEARLALDG ETLGEEEQED EQPPWASPSP TSRQSPASPP PLGGGAPVRT 480
AKAERRHQER LRVQSPEPPA PERALSPAEL RALEAEKRAL WRAARMKSLE QDALRAQMVL 540
SRSQEGRGTR GPLERLAEAP SPAPTPSPTP VEDLGPQTST SPGRLSPDFA EELRSLEPSP 600
SPGPQEEDGE VALVLLGRPS PGAVGPEDVA LCSSRRPVRP GRRGLGPVPS 650 
Gene Ontology
  
Interpro
 IPR001478; PDZ. 
Pfam
 PF00595; PDZ 
SMART
 SM00228; PDZ 
PROSITE
 PS50106; PDZ 
PRINTS