| Tag | Content |
|---|
| CPLM ID | CPLM-001347 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Cadherin-16 |
Protein Synonyms/Alias | Kidney-specific cadherin; Ksp-cadherin |
Gene Name | Cdh16 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 815 | THLALARKDLDQPAD | ubiquitination | [1] | | 827 | PADSVPLKAAV**** | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. |
Sequence Annotation | DOMAIN 27 128 Cadherin 1.
DOMAIN 133 237 Cadherin 2.
DOMAIN 244 338 Cadherin 3.
DOMAIN 343 451 Cadherin 4.
DOMAIN 457 566 Cadherin 5.
DOMAIN 571 667 Cadherin 6.
REGION 668 788 Ectodomain G.
CARBOHYD 519 519 N-linked (GlcNAc...) (Potential).
CARBOHYD 604 604 N-linked (GlcNAc...) (Potential).
CARBOHYD 724 724 N-linked (GlcNAc...) (Potential). |
Keyword | Calcium; Cell adhesion; Cell membrane; Complete proteome; Glycoprotein; Membrane; Metal-binding; Reference proteome; Repeat; Signal; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 830 AA |
Protein Sequence | MISARPWLLY LSVIQAFTTE AQPAESLHTE VPENYGGNFP FYILKLPLPL GRDEGHIVLS 60
GDSNTADQNT FAVDTDSGFL VATRTLDREE KAEYQLQVTL ESEDGRILWG PQLVTVHVKD 120
ENDQVPQFSQ AIYRAQLSQG TRPGVPFLFL EASDGDAPGT ANSDLRFHIL SQSPPQPLPD 180
MFQLDPHLGA LALSPSGSTS LDHALEETYQ LLVQVKDMGD QPSGHQAIAT VEISIVENSW 240
APLEPVHLAE NLKVVYPHSI AQVHWSGGDV HYQLESQPPG PFDVDTEGML HVTMELDREA 300
QAEYQLQVRA QNSHGEDYAE PLELQVVVMD ENDNAPVCSP HDPTVNIPEL SPPGTEIARL 360
SAEDLDAPGS PNSHIVYQLL SPEPEEGAEN KAFELDPTSG SVTLGTAPLH AGQSILLQVL 420
AVDLAGSESG LSSTCEVTVM VTDVNNHAPE FINSQIGPVT LPEDVKPGAL VATLMATDAD 480
LEPAFRLMDF AIEEGDPEGI FDLSWEPDSD HVQLRLRKNL SYEAAPDHKV VVVVSNIEEL 540
VGPGPGPAAT ATVTILVERV VAPLKLDQES YETSIPVSTP AGSLLLTIQP SDPMSRTLRF 600
SLVNDSEGWL CIKEVSGEVH TAQSLQGAQP GDTYTVLVEA QDTDKPGLST SATVVIHFLK 660
ASPVPALTLS AGPSRHLCTP RQDYGVVVSG VSEDPDLANR NGPYSFALGP NPTVQRDWRL 720
QPLNDSHAYL TLALHWVEPG EYMVPVVVHH DTHMWQLQVK VIVCRCNVEG QCMRKVGRMK 780
GMPTKLSAVG VLLGTLAAIG FILILVFTHL ALARKDLDQP ADSVPLKAAV 830 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. GO:0005509; F:calcium ion binding; IEA:InterPro. GO:0007156; P:homophilic cell adhesion; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |