CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031845
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 UvrD/REP helicase domain-containing protein 
Protein Synonyms/Alias
 UvrD/REP helicase domain-containing protein, putative 
Gene Name
 TGME49_077550, TGVEG_028300 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Toxoplasma gondii 
NCBI Taxa ID
 5811 
Lysine Modification
Position
Peptide
Type
References
86SAAVFASKGIPGRKTacetylation[1]
Reference
 [1] Lysine acetylation is widespread on proteins of diverse function and localization in the protozoan parasite Toxoplasma gondii.
 Jeffers V, Sullivan WJ Jr.
 Eukaryot Cell. 2012 Jun;11(6):735-42. [PMID: 22544907
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Helicase; Hydrolase; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2851 AA 
Protein Sequence
MSEAGDQNSR TPGVSANASS VSVEQMRLLP REGQKSSDAR DAGSANQECP RTSQTPSLER 60
LPAPLPTGLA STTLLREGSA AVFASKGIPG RKTSENKSSL SPPGAVSHSV TQQRPAPHRS 120
RPLWTSGVWT PHHEADREEG REGLGSCASS NAERNAVRSG TRETELKGRK EEESRALSRT 180
EMKTNPSPAR TSGSPQNRPR QPRPPVSSGF HPASAPFHSR PLGASPSSIS PSSSSSLSSY 240
SCASSSSSSS LSSYSCASSS SSSPSSSSPL STASRPSATS GPAVSLVGAT GLRVPANSTV 300
PACGASASLA SHPVSSEEER RRSVAMVRSL SSAAVSSFQS SFVPSACVQS SPTPACASSR 360
PPASSFSSLS ASLASSAASS TRLASDPSQS SLSSQSLHSS HSLHSSLPSS LPWTSPGRSR 420
GLSSAVPLSP SAPRLHSESS DGTEKPPAAF GLPAGDSLPS ASRELLRRSI PFNASSLGGG 480
KTQPPSSRSA TLPSSAPSSF ASATTRDPGV SPSRHTSDFS RPVVVRCSSP SSSPSPSRAS 540
TPAPSSPVLP SAASSASSYV LVSSLRPPRR PSAFLKPSVI SSASLPSLPG SAGGASSESS 600
AIFQSDTDAM ETTRGGNGQQ CEDKDRNQNG LYVDERARRR RTPVVRAHEA KKEGGKRMRS 660
DGEEREREAE GLAFRAVLPE KAKGTRREET EEEVCLKEEA KEEGDAEKAV RICEAEKLLP 720
PHSKIFGQLS EEQRRVVLAP AHANLCVIAG PGSGKTTAIT ARILRLLLEG EGPILALTFT 780
RRGAEELRTR VVDGFSSTLA EMRLLSGSRE NGALPSAVSP RTNAATSSTA SARTNGGDAT 840
IFNAPLAKLD WQRQTNWTHP FAPASAAGPH PRCDSAPVHP SVTCYSSSAV APSASASFAS 900
LSASLGEQAP TSAAAAPGLP LFHDLAGRVL VGTFHKFGLL VLRRHGRAVG VPPSFLVATA 960
TRQGQLAREV LEAFKAREEA RGAMLKSARE EPGRPQRACG VGNLEAAFQQ VRRLHLLRMQ 1020
RELAERQRER AARSRGGGPE TAESRATGKT GETGEADICL DEAALDSDPD DLLDFLTDEE 1080
EEESGGFHSQ HSGLPAAGRT TRREPGEACG GRQPSRGPVA PHMGSRVGST KSRTTWKEVD 1140
MFLRLVRKCK FSEAFLDTLK TENAQLYALT RQYAALLRQQ TPPLLDCSDL ILLTLALLES 1200
QPNIRRDLAT AYPIVVVDEF QDTSLPQFKV VKALALGRQE QEREQARERA WMHETMERER 1260
GEGRAGFCAG NPGRQEATRQ RRGGVTVVGD DDQSIYGFRG IDAKNFLIFD RAFPDRLEFH 1320
LSCNYRSVAP IVSASLALIN HNRHRRLKRL YPAARPFSSF LSSFLFQAVL PPHQMPSPPL 1380
GSASAAIHYT PSHQANALTN SSAAASSCPP SAPGCSSAAA SSTPSSSSSS CSSLASSPSP 1440
SAGLLSLFPP AMCAVLSSPK AEAAYILRFI VALKQTRKLC WGDFVILSRT NRGLKELEEL 1500
LQDPQVLHSA FRSSPLPDAG PLPILSLSPS LGEDEVENQR ASSSASSPSS LAAPRSPLAS 1560
LSSTLCLSPV TSPPSLWYRP DRPPDPSLLC PLWASSAFPE ALPLHSTALK RRGTQMLRKQ 1620
GVLLVCGYLR LALDPHHDAS FLRVLNRPRR GLGLAVVRAL CRCLQTLEGD AASPAEAGKP 1680
RSEAGNEETD AAEEVEEGER EGVEREGEGK GGRRRKRGRE ARAQEGARQD GEEGEEGEGG 1740
GRRKEAVTKS LVCWDAKWRE GPLEGIDRLR KHERQCDAHR GSRVFSLYEA ASIIAELEET 1800
AENGEGERKR NDETNTQQEG EAGTSSRSSS SSSANPSFST PSPSVSSVSG SSPSSVDLPV 1860
EDHATERLSR EKKETRLLSG SLLKQTKCPA SALPRLRRFL EQLQALRSLA RSRTAGASDL 1920
VLFVLKAFGL EAFLAGVSGE TEGTETLPKT ETEKQTTETA DQKTLERRKE RAEKKKGRKK 1980
AAGAGRDDGD EVCRQAEEET WGECGAGEKR GDSAVRASGE GTEREMQAKK LRKKNDGPDR 2040
EKRTPIEEKR QTEKRDRESK TDPTSSTSVC SSENKLEDAW TLLRLAEGYT PNALQPTGWD 2100
CLSRFLKDLT NDRCGEAETL QRRNSIFLST IHQAKGLEWP VVILAKANEG ASSSASSSSS 2160
FVLVPPLSSS SSAAASAVSS VSAVSASLTA EAWQKRRTQE ERVWAMWTEK KKLEEQELEE 2220
ERRLCYVALT RAKSMLLVTC SKTEKSGQSL RVSRFVSEAK LFHFHPLSAA SGVHPKSEKD 2280
PCRCRSAGTS TDARGSREEE TETDRDAHAE RRKREERNSQ LGHRVAKGRL QEEGETGGNE 2340
EESLTKGKLT AEGQKKEEDW TGETKAHQNG TDTESERNRE MKMKGEHDAS EEDIKIDTDI 2400
SDLLDLSSVS ERTGQWGRLL EARKKQQQNR SSSFRCTSPS FGRLAAPSAA SHSVSVSNEG 2460
VRPVSDESSS SPSELAKALP AGALGEGRRP SRCGDLSRGE TLDASSEGEE LKKHAGERES 2520
EERSRTPSPT EGPARREVIE EASERRGGDP RAAEEKRREE TKAEQDEEKL LPSTCAPKRE 2580
EQYERRNAED TQREEASQRD AQEAEAEEEL QRKEESRNSN RQTLEMYAFE PEDDEVISLG 2640
SDLDEPTAGP MDPCRDAPTP GKEPEGKRRS EIACSSHAEI REVVTALEEA EEETGEEGEE 2700
TGNAIAEKEN YEQPTAEEKD ERVDVREQSK DSREKETRQT PRVARKATER RDGEADVIVI 2760
DEEEAPETAH DRETEKTQET TAEPDSVSKG EDEMEEPTAV EVEDDDEVEA QRDQDESSAL 2820
SSSGRLEAPA RSLGSAAAPG RPWRCFLLKK K 2851 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0008854; F:exodeoxyribonuclease V activity; IEA:EC.
 GO:0004386; F:helicase activity; IEA:UniProtKB-KW. 
Interpro
 IPR014017; DNA_helicase_UvrD-like_C.
 IPR027417; P-loop_NTPase.
 IPR014016; UvrD-like_ATP-bd. 
Pfam
 PF00580; UvrD-helicase
 PF13361; UvrD_C 
SMART
  
PROSITE
 PS51198; UVRD_HELICASE_ATP_BIND
 PS51217; UVRD_HELICASE_CTER 
PRINTS