CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026880
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 HSP90AB1 protein 
Protein Synonyms/Alias
  
Gene Name
 HSP90AB1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
53NASDALDKIRYESLTubiquitination[1]
69PSKLDSGKELKIDIIubiquitination[1]
95DTGIGMTKADLINNLubiquitination[1]
107NNLGTIAKSGTKAFMubiquitination[1]
180EPIGRGTKVILHLKEubiquitination[1]
204RVKEVVKKHSQFIGYubiquitination[1]
219PITLYLEKEREKEISubiquitination[1]
275KTKKIKEKYIDQEELubiquitination[1]
284IDQEELNKTKPIWTRubiquitination[1]
286QEELNKTKPIWTRNPubiquitination[1]
306EEYGEFYKSLTNDWEubiquitination[1]
346APFDLFEKKKKKK**ubiquitination[1]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 351 AA 
Protein Sequence
MPEEVHHGEE EVETFAFQAE IAQLMSLIIN TFYSNKEIFL RELISNASDA LDKIRYESLT 60
DPSKLDSGKE LKIDIIPNPQ ERTLTLVDTG IGMTKADLIN NLGTIAKSGT KAFMEALQAG 120
ADISMIGQFG VGFYSAYLVA EKVVVITKHN DDEQYAWESS AGGSFTVRAD HGEPIGRGTK 180
VILHLKEDQT EYLEERRVKE VVKKHSQFIG YPITLYLEKE REKEISDDEA EEEKGEKEEE 240
DKDDEEKPKI EDVGSDEEDD SGKDKKKKTK KIKEKYIDQE ELNKTKPIWT RNPDDITQEE 300
YGEFYKSLTN DWEDHLAVKH FSVEGQLEFR ALLFIPRRAP FDLFEKKKKK K 351 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0006457; P:protein folding; IEA:InterPro.
 GO:0006950; P:response to stress; IEA:InterPro. 
Interpro
 IPR003594; HATPase_ATP-bd.
 IPR019805; Heat_shock_protein_90_CS.
 IPR001404; Hsp90.
 IPR020575; Hsp90_N.
 IPR020568; Ribosomal_S5_D2-typ_fold. 
Pfam
 PF02518; HATPase_c
 PF00183; HSP90 
SMART
 SM00387; HATPase_c 
PROSITE
 PS00298; HSP90 
PRINTS
 PR00775; HEATSHOCK90.