CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026046
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein Serpinc1 
Protein Synonyms/Alias
 Serine (Or cysteine) peptidase inhibitor, clade C (Antithrombin), member 1 
Gene Name
 Serpinc1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
209KLQPLDFKENPEQSRacetylation[1]
436NPSRVTFKANRPFLVacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 465 AA 
Protein Sequence
MYSPGIGSAV AGERKLCLLS LLLIGALGCA VCHGNPVDDI CIAKPRDIPV NPMCIYRSPA 60
KKATEEDVLE QKVPEATNRR VWELSKANSR FATNFYQHLA DSKNDNDNIF LSPLSISTAF 120
AMTKLGACNN TLKQLMEVFK FDTISEKTSD QIHFFFAKLN CRLYRKANKS SNLVSANRLF 180
GDKSLTFNES YQDVSEIVYG AKLQPLDFKE NPEQSRVTIN NWVANKTEGR IKDVIPQGAI 240
DELTALVLVN TIYFKGLWKS KFSPENTRKE PFHKVDGQSC LVPMMYQEGK FKYRRVGEGT 300
QVLEMPFKGD DITMVLILPK PEKSLAKVEQ ELTPELLQEW LDELSEVMLV VHVPRFRIED 360
SFSLKEQLQD MGLVDLFSPE KSQLPGIIAE GRDDLFVSDA FHKAFLEVNE EGSEAAASTS 420
VVITGRSLNP SRVTFKANRP FLVLIREVAL NTIIFMGRVS NPCVN 465 
Gene Ontology
 GO:0005615; C:extracellular space; IDA:RGD.
 GO:0008201; F:heparin binding; IDA:RGD.
 GO:0004867; F:serine-type endopeptidase inhibitor activity; IDA:RGD.
 GO:0050728; P:negative regulation of inflammatory response; IMP:RGD.
 GO:0030162; P:regulation of proteolysis; IBA:RefGenome.
 GO:0007584; P:response to nutrient; IDA:RGD. 
Interpro
 IPR015555; AT-III.
 IPR023795; Protease_inhib_I4_serpin_CS.
 IPR023796; Serpin_dom.
 IPR000215; Serpin_fam. 
Pfam
 PF00079; Serpin 
SMART
 SM00093; SERPIN 
PROSITE
 PS00284; SERPIN 
PRINTS