CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032188
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Tripartite motif-containing protein 46 
Protein Synonyms/Alias
 cDNA FLJ55765, highly similar to Tripartite motif-containing protein 46 
Gene Name
 TRIM46 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
48PVCQEMYKQPLVLPCubiquitination[1]
114DRLDRLLKSGFGTYPubiquitination[1]
206TFCNECFKLFHPWGTubiquitination[1]
317EVSGQQAKEEVSQLVubiquitination[1]
334LGAVLEEKRASLLQAubiquitination[1]
426LDVGREMKLLTELNFubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 505 AA 
Protein Sequence
MRRGGILGHR PGPQAFLVPG ASAATLYKTS MKNMEKELLC PVCQEMYKQP LVLPCTHNVC 60
QACAREVLGQ QGYIGHGGDP SSEPTSPAST PSTRSPRLSR RTLPKPDRLD RLLKSGFGTY 120
PGRKRGALHP QVIMFPCPAC QGDVELGERG LAGLFRNLTL ERVVERYRQS VSVGGAILCQ 180
LCKPPPLEAT KGCTECRATF CNECFKLFHP WGTQKAQHEP TLPTLSFRPK GLMCPDHKEE 240
VTHYCKTCQR LVCQLCRVRR THSGHKITPV LSAYQALKDK LTKSLTYILG NQDTVQTQIC 300
ELEEAVRHTE VSGQQAKEEV SQLVRGLGAV LEEKRASLLQ AIEECQQERL ARLSAQIQEH 360
RSLLDGSGLV GYAQEVLKET DQPCFVQAAK QLHNRIARAT EALQTFRPAA SSSFRHCQLD 420
VGREMKLLTE LNFLRGCGHR GLCSGAPQCL RPPSLTPSAP LPMIRSSCAG GCPPIHHLPG 480
TIPLSSGARM CLLSQAPPAG SGGRR 505 
Gene Ontology
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR017903; COS_domain.
 IPR000315; Znf_B-box.
 IPR018957; Znf_C3HC4_RING-type.
 IPR001841; Znf_RING.
 IPR013083; Znf_RING/FYVE/PHD.
 IPR017907; Znf_RING_CS. 
Pfam
 PF00643; zf-B_box
 PF00097; zf-C3HC4 
SMART
 SM00336; BBOX
 SM00184; RING 
PROSITE
 PS51262; COS
 PS50119; ZF_BBOX
 PS00518; ZF_RING_1 
PRINTS