UniProt Accession

 MYG1_HUMAN; Q9HB07 

Genbank Protein ID

 AF289485; AC073611 

Genbank Nucleotide ID

 AAG17847.1 

Protein Name

 UPF0160 protein MYG1, mitochondrial 

Protein Synonyms/Alias

  

Gene Name

 C12orf10 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
123	MSSLSPGKPWQTKLS	ubiquitination	[1]
218	QDTEAGFKRAMDLVQ	ubiquitination	[1, 2]
267	GEIVELAKGACPWKE	acetylation	[3]
267	GEIVELAKGACPWKE	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [3] Lysine acetylation targets protein complexes and co-regulates major cellular functions.
 Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M.
 Science. 2009 Aug 14;325(5942):834-40. [PMID: 19608861] 

Functional Description

  

Sequence Annotation

 MOD_RES 267 267 N6-acetyllysine.  

Keyword

 Acetylation; Complete proteome; Mitochondrion; Nucleus; Polymorphism; Reference proteome; Transit peptide. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 376 AA 

Protein Sequence

Gene Ontology

 GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0043473; P:pigmentation; NAS:UniProtKB. 

Interpro

 IPR003226; Met-dep_prot_hydro. 

Pfam

 PF03690; UPF0160 

SMART

  

PROSITE

  

PRINTS