CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041722
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cathelicidin antimicrobial peptide 
Protein Synonyms/Alias
 Protein Camp 
Gene Name
 Camp 
Gene Synonyms/Alias
 rCG_25558 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
150LLRKGGEKFGEKLRKacetylation[1]
163RKIGQKIKDFFQKLAacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Secreted. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 175 AA 
Protein Sequence
MQPHRDVPSL WRSLSLLLLL GLGLPLAVSQ TLSYREAVLR AVDDFNQQSL DTNLYRLLDL 60
DSEPQGDEDP DTPKYVRFRV KETVCSKASQ QLPEQCAFKE QGVVKQCMGT VTLNQAAESF 120
DISCDAPGIQ PFRFKKISRL AGLLRKGGEK FGEKLRKIGQ KIKDFFQKLA PEIEQ 175 
Gene Ontology
 GO:0042995; C:cell projection; IDA:RGD.
 GO:0005737; C:cytoplasm; IDA:RGD.
 GO:0005615; C:extracellular space; IDA:RGD.
 GO:0042581; C:specific granule; IEA:Compara.
 GO:0004869; F:cysteine-type endopeptidase inhibitor activity; IEA:InterPro.
 GO:0071347; P:cellular response to interleukin-1; IEP:RGD.
 GO:0071354; P:cellular response to interleukin-6; IEP:RGD.
 GO:0071222; P:cellular response to lipopolysaccharide; IEP:RGD.
 GO:0071224; P:cellular response to peptidoglycan; IEP:RGD.
 GO:0071356; P:cellular response to tumor necrosis factor; IEP:RGD.
 GO:0050829; P:defense response to Gram-negative bacterium; IMP:RGD.
 GO:0050830; P:defense response to Gram-positive bacterium; IMP:RGD.
 GO:0051873; P:killing by host of symbiont cells; IEA:Compara.
 GO:0044130; P:negative regulation of growth of symbiont in host; IEA:Compara.
 GO:0044140; P:negative regulation of growth of symbiont on or near host surface; IEA:Compara.
 GO:0045766; P:positive regulation of angiogenesis; IMP:RGD.
 GO:0008284; P:positive regulation of cell proliferation; IMP:RGD.
 GO:0001934; P:positive regulation of protein phosphorylation; IMP:RGD. 
Interpro
 IPR001894; Cathelicidin.
 IPR018216; Cathelicidin_CS.
 IPR022746; Cathlecidin_C.
 IPR000010; Prot_inh_cystat. 
Pfam
 PF12153; CAP18_C
 PF00666; Cathelicidins 
SMART
 SM00043; CY 
PROSITE
 PS00946; CATHELICIDINS_1
 PS00947; CATHELICIDINS_2 
PRINTS