CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042367
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 AT-rich interactive domain-containing protein 1A 
Protein Synonyms/Alias
  
Gene Name
 ARID1A 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
127RMSYEPNKDPYGSMRacetylation[1]
559QRRRLTMKDIGTPEAacetylation[2]
559QRRRLTMKDIGTPEAubiquitination[2, 3]
705SEEKLISKFDKLPVKacetylation[2]
712KFDKLPVKIVQKNDPubiquitination[2]
727FVVDCSDKLGRVQEFacetylation[2]
727FVVDCSDKLGRVQEFubiquitination[2, 4]
802PPDGPPEKRITATMDacetylation[1, 2]
876DWQDSLAKRCVCVSNubiquitination[4]
917KLILLHHKHPERKQAubiquitination[4]
1043PPFSRLEKLYSTMVRubiquitination[3]
Reference
 [1] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [4] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1182 AA 
Protein Sequence
XECKIERGED PPPDIFAAAD SKKSQPKIQP PSPAGSGSMQ GPQTPQSTSS SMAEGGDLKP 60
PTPASTPHSQ IPPLPGMRSN SVGIQDAFND GSDSTFQKRN SMTPNPGYQP SMNTSDMMGR 120
MSYEPNKDPY GSMRKAPGSD PFMSSGQGPN GGMGDPYSRA AGPGLGNVAM GPRQHYPYGG 180
PYDRVRTEPG IGPEGNMSTG APQPNLMPSN PDSGMYSPSR YPPQQQQQQQ QRHDSYGNQF 240
STQGTPSGSP FPSQQTTMYQ QQQQNYKRPM DGTYGPPAKR HEGEMYSVPY STGQGQPQQQ 300
QLPPAQPQPA SQQQAAQPSP QQDVYNQYGN AYPATATAAT ERRPAGGPQN QFPFQFGRDR 360
VSAPPGTNAQ QNMPPQMMGG PIQASAEVAQ QGTMWQGRND MTYNYANRQS TGSAPQGPAY 420
HGVNRTDEML HTDQRANHEG SWPSHGTRQP PYGPSAPVPP MTRPPPSNYQ PPPSMQNHIP 480
QVSSPAPLPR PMENRTSPSK SPFLHSGMKM QKAGPPVPAS HIAPAPVQPP MIRRDITFPP 540
GSVEATQPVL KQRRRLTMKD IGTPEAWRVM MSLKSGLLAE STWALDTINI LLYDDNSIMT 600
FNLSQLPGLL ELLVEYFRRC LIEIFGILKE YEVGDPGQRT LLDPGRFSKV SSPAPMEGGE 660
EEEELLGPKL EEEEEEEVVE NDEEIAFSGK DKPASENSEE KLISKFDKLP VKIVQKNDPF 720
VVDCSDKLGR VQEFDSGLLH WRIGGGDTTE HIQTHFESKT ELLPSRPHAP CPPAPRKHVT 780
TAEGTPGTTD QEGPPPDGPP EKRITATMDD MLSTRSSTLT EDGAKSSEAI KESSKFPFGI 840
SPAQSHRNIK ILEDEPHSKD ETPLCTLLDW QDSLAKRCVC VSNTIRSLSF VPGNDFEMSK 900
HPGLLLILGK LILLHHKHPE RKQAPLTYEK EEEQDQGVSC NKVEWWWDCL EMLRENTLVT 960
LANISGQLDL SPYPESICLP VLDGLLHWAV CPSAEAQDPF STLGPNAVLS PQRLVLETLS 1020
KLSIQDNNVD LILATPPFSR LEKLYSTMVR FLSDRKNPVC REMAVVLLAN LAQGDSLAAR 1080
AIAVQKGSIG NLLGFLEDSL AATQFQQSQA SLLHMQNPPF EPTSVDMMRR AARALLALAK 1140
VDENHSEFTL YESRLLDISV SPLMNSLVSQ VICDVLFLIG QS 1182 
Gene Ontology
 GO:0005634; C:nucleus; IDA:HPA. 
Interpro
 IPR021906; DUF3518. 
Pfam
 PF12031; DUF3518 
SMART
  
PROSITE
  
PRINTS