| Tag | Content |
|---|
| CPLM ID | CPLM-019619 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Ras-related protein Rab-40C |
Protein Synonyms/Alias | Rar-like protein; Ras-like protein family member 8C; SOCS box-containing protein RAR3 |
Gene Name | RAB40C |
Gene Synonyms/Alias | RARL; RASL8C |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 211 | TPVHLIDKLPLPVTI | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. |
Sequence Annotation | DOMAIN 175 228 SOCS box.
NP_BIND 21 28 GTP (By similarity).
NP_BIND 69 73 GTP (By similarity).
NP_BIND 126 129 GTP (By similarity).
LIPID 273 273 S-palmitoyl cysteine (Potential).
LIPID 278 278 S-geranylgeranyl cysteine (By |
Keyword | Cell membrane; Complete proteome; GTP-binding; Lipoprotein; Membrane; Nucleotide-binding; Palmitate; Prenylation; Reference proteome; Ubl conjugation pathway. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 281 AA |
Protein Sequence | MGSQGSPVKS YDYLLKFLLV GDSDVGKGEI LESLQDGAAE SPYAYSNGID YKTTTILLDG 60
RRVKLELWDT SGQGRFCTIF RSYSRGAQGI LLVYDITNRW SFDGIDRWIK EIDEHAPGVP 120
RILVGNRLHL AFKRQVPTEQ ARAYAEKNCM TFFEVSPLCN FNVIESFTEL SRIVLMRHGM 180
EKIWRPNRVF SLQDLCCRAI VSCTPVHLID KLPLPVTIKS HLKSFSMANG MNAVMMHGRS 240
YSLASGAGGG GSKGNSLKRS KSIRPPQSPP QNCSRSNCKI S 281 |
Gene Ontology | GO:0048471; C:perinuclear region of cytoplasm; IEA:Compara. GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. GO:0019003; F:GDP binding; IEA:Compara. GO:0005525; F:GTP binding; IEA:UniProtKB-KW. GO:0015031; P:protein transport; IEA:InterPro. GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway. GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |