CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038427
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Low affinity immunoglobulin gamma Fc region receptor II 
Protein Synonyms/Alias
  
Gene Name
 Fcgr2b 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
295TITYSLLKHPEALDEubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 312 AA 
Protein Sequence
MGILPFLLIP MESNWTVHVF SRTLCHMLLW TAVLNLAAGT HDLPKAVVKL EPPWIQVLKE 60
DTVTLTCEGT HNPGNSSTQW FHNGRSIRSQ VQASYTFKAT VNDSGEYRCQ MEQTRLSDPV 120
DLGVISDWLL LQTPQLVFLE GETITLRCHS WRNKLLNRIS FFHNEKSVRY HHYSSNFSIP 180
KANHSHSGDY YCKGSLGRTL HQSKPVTITV QGPKSSRSLP VLTIVAAVTG IAVAAIVIIL 240
VSLVYLKKKQ VPALPGNPDH REMGETLPEE VDNPPDLEEA AKTEAENTIT YSLLKHPEAL 300
DEETEHDYQN HI 312 
Gene Ontology
 GO:0009897; C:external side of plasma membrane; IDA:MGI.
 GO:0005887; C:integral to plasma membrane; IC:MGI.
 GO:0019864; F:IgG binding; IDA:MGI.
 GO:0005057; F:receptor signaling protein activity; TAS:MGI.
 GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; IMP:MGI.
 GO:0007166; P:cell surface receptor signaling pathway; IMP:MGI.
 GO:0071219; P:cellular response to molecule of bacterial origin; IMP:MGI.
 GO:0006952; P:defense response; IMP:MGI.
 GO:0016064; P:immunoglobulin mediated immune response; IMP:MGI.
 GO:0030889; P:negative regulation of B cell proliferation; IMP:MGI.
 GO:0002924; P:negative regulation of humoral immune response mediated by circulating immunoglobulin; IMP:MGI.
 GO:0002638; P:negative regulation of immunoglobulin production; IMP:MGI.
 GO:0032693; P:negative regulation of interleukin-10 production; IMP:MGI.
 GO:0050765; P:negative regulation of phagocytosis; IMP:MGI.
 GO:0001811; P:negative regulation of type I hypersensitivity; IMP:MGI.
 GO:0006911; P:phagocytosis, engulfment; IDA:MGI.
 GO:0050766; P:positive regulation of phagocytosis; IDA:MGI. 
Interpro
 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR003599; Ig_sub. 
Pfam
  
SMART
 SM00409; IG 
PROSITE
 PS50835; IG_LIKE 
PRINTS