UniProt Accession

 RL3_ECOLI; P60438; P02386; Q2M6Y5 

Genbank Protein ID

 X02613; U18997; U00096; AP009048; V00344 

Genbank Nucleotide ID

 CAA26460.1; AAA58117.1; AAC76345.1; BAE77971.1; CAA23634.1 

Protein Name

 50S ribosomal protein L3 

Protein Synonyms/Alias

  

Gene Name

 rplC 

Gene Synonyms/Alias

 b3320; JW3282 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
38	ANRVTQVKDLANDGY	acetylation	[1]
62	KKANRVTKPEAGHFA	acetylation	[1]
70	PEAGHFAKAGVEAGR	acetylation	[1]
106	ELFADVKKVDVTGTS	acetylation	[2]
190	ERNLLLVKGAVPGAT	acetylation	[1]
204	TGSDLIVKPAVKA**	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618]
 [2] Comprehensive profiling of protein lysine acetylation in Escherichia coli.
 Zhang K, Zheng S, Yang JS, Chen Y, Cheng Z.
 J Proteome Res. 2013 Feb 1;12(2):844-51. [PMID: 23294111] 

Functional Description

 One of two assembly inititator proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. 

Sequence Annotation

 MOD_RES 38 38 N6-succinyllysine.
 MOD_RES 150 150 N5-methylglutamine.  

Keyword

 3D-structure; Complete proteome; Direct protein sequencing; Methylation; Reference proteome; Ribonucleoprotein; Ribosomal protein; RNA-binding; rRNA-binding. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 209 AA 

Protein Sequence

Gene Ontology

 GO:0005840; C:ribosome; IEA:UniProtKB-KW.
 GO:0019843; F:rRNA binding; IEA:HAMAP.
 GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
 GO:0006412; P:translation; IEA:HAMAP. 

Interpro

 IPR000597; Ribosomal_L3.
 IPR019927; Ribosomal_L3_bac/org-type.
 IPR019926; Ribosomal_L3_CS.
 IPR009000; Transl_elong_init/rib_B-barrel. 

Pfam

 PF00297; Ribosomal_L3 

SMART

  

PROSITE

 PS00474; RIBOSOMAL_L3 

PRINTS