CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032846
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein inhibitor of activated STAT 1 
Protein Synonyms/Alias
  
Gene Name
 PIAS1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
8MADSAELKQMVMSLRubiquitination[1]
46TKALHLLKAGCSPAVubiquitination[1]
Reference
 [1] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724] 
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 325 AA 
Protein Sequence
MADSAELKQM VMSLRVSELQ VLLGYAGRNK HGRKHELLTK ALHLLKAGCS PAVQMKIKEL 60
YRRRFPQKIM TPADLSIPNV HSSPMPATLS PSTIPQLTYD GHPASSPLLP VSLLGPKHEL 120
ELPHLTSALH PVHPDIKLQK LPFYDLLDEL IKPTSLASDN SQRFRETCFA FALTPQQVQQ 180
ISSSMDISGT KCDFTVQVQL RFCLSETSCP QEDHFPPNLC VKVNTKPCSL PGYLPPTKNG 240
VEPKRPSRPI NITSLVRLST TVPNTIVVSW TAEIGRNYSM AVYLVKQLSS TVLLQRLRAK 300
GIRNPDHSRA LSTYDKLISL IQLFC 325 
Gene Ontology
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0019789; F:SUMO ligase activity; IEA:InterPro. 
Interpro
 IPR027227; PIAS1.
 IPR023321; PINIT.
 IPR003034; SAP_dom. 
Pfam
 PF14324; PINIT 
SMART
 SM00513; SAP 
PROSITE
 PS51466; PINIT
 PS50800; SAP 
PRINTS