CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033761
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase-2 variant 7 
Protein Synonyms/Alias
 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 
Gene Name
 Pfkfb2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
148DMILNFAKQNAFKVFacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Hydrolase; Kinase; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 197 AA 
Protein Sequence
MSENSTFSTE DSSSSSYKPH ASNLRRAGKK CSWASYMTNS PTLIVMIGLP ARGKTYVSKK 60
LTRYLNWIGV PTKVFNLGVY RREAVKSYKS YDFFRHDNEE AMKIRKQCAL VALEDVKAYF 120
TEESGQIAVF DATNTTRERR DMILNFAKQN AFKVFFVESV CDDPDVIAAN ILGPLVHKGD 180
ECRPEVSGQQ SSGLHPE 197 
Gene Ontology
 GO:0003873; F:6-phosphofructo-2-kinase activity; IEA:EC.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0004331; F:fructose-2,6-bisphosphate 2-phosphatase activity; IEA:EC.
 GO:0006003; P:fructose 2,6-bisphosphate metabolic process; IEA:InterPro.
 GO:0006000; P:fructose metabolic process; IEA:InterPro. 
Interpro
 IPR003094; 6Pfruct_kin.
 IPR013079; 6Phosfructo_kin.
 IPR027417; P-loop_NTPase. 
Pfam
 PF01591; 6PF2K 
SMART
  
PROSITE
  
PRINTS
 PR00991; 6PFRUCTKNASE.