CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017172
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Copine-5 
Protein Synonyms/Alias
 Copine V 
Gene Name
 Cpne5 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
102DLYDVDSKSPDLSKHubiquitination[1]
196DKKDFFGKSDPFLVFubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 May function in membrane trafficking. Exhibits calcium- dependent phospholipid binding properties (By similarity). 
Sequence Annotation
 DOMAIN 9 116 C2 1.
 DOMAIN 147 268 C2 2.
 DOMAIN 328 554 VWFA.
 MOD_RES 19 19 Phosphoserine (By similarity).  
Keyword
 Complete proteome; Phosphoprotein; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 593 AA 
Protein Sequence
MEQPEDMASL SEFDSLAGSI PATKVEITVS CRNLLDKDMF SKSDPLCVMY TQGMENKQWR 60
EFGRTEVIDN TLNPDFVRKF IVDYFFEEKQ NLRFDLYDVD SKSPDLSKHD FLGQAFCTLG 120
EIVGSSGSRL EKPLTIGTFS LNSRTGKPMP AVSNGGVPGK KCGTIILSAE ELSNCRDVAT 180
MQFCANKLDK KDFFGKSDPF LVFYRSNEDG TFTICHKTEV MKNTLNPVWQ TFSIPVRALC 240
NGDYDRTIKV EVYDWDRDGS HDFIGEFTTS YRELARGQSQ FNIYEVINPK KKMKKKKYVN 300
SGTVTLLSFA VESESTFLDY IKGGTQINFT VAIDFTASNG NPSQSTSLHY MSPYQLNAYA 360
LALTAVGEII QHYDSDKMFP ALGFGAKLPP DGRVSHEFPL NGNQENPSCC GIDGILEAYH 420
SSLRTVQLYG PTNFAPVVTH VARNAAAVQD GSQYSVLLII TDGVISDMAQ TKEAIVNAAK 480
LPMSIIIVGV GQAEFDAMVE LDGDDVRISS RGKLAERDIV QFVPFRDYVD RTGNHVLSMA 540
RLARDVLAEI PDQLVSYMKA QGIRPRPPPA APAQSPPQSP AHSPPGSPVH THI 593 
Gene Ontology
 GO:0043005; C:neuron projection; IDA:MGI.
 GO:0043025; C:neuronal cell body; IDA:MGI. 
Interpro
 IPR000008; C2_Ca-dep.
 IPR008973; C2_Ca/lipid-bd_dom_CaLB.
 IPR018029; C2_membr_targeting.
 IPR010734; Copine.
 IPR002035; VWF_A. 
Pfam
 PF00168; C2
 PF07002; Copine 
SMART
 SM00239; C2
 SM00327; VWA 
PROSITE
 PS50004; C2
 PS50234; VWFA 
PRINTS