UniProt Accession

 OSTB_YEAST; P33767; D3DLP5 

Genbank Protein ID

 X61388; U18530; BK006939 

Genbank Nucleotide ID

 CAA43660.1; AAB64479.1; DAA07649.1 

Protein Name

 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1 

Protein Synonyms/Alias

 Oligosaccharyl transferase subunit WBP1; Oligosaccharyl transferase subunit beta 

Gene Name

 WBP1 

Gene Synonyms/Alias

 YEL002C 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
85	NIIVFPTKGGKNLAR	ubiquitination	[1]
136	LGIYPSPKGHVIRDY	ubiquitination	[1]
168	KYVYNARKSEDFVFG	ubiquitination	[1]
203	RTSFTESKGKCNSWT	ubiquitination	[1]
241	SSDFLKNKNQDSNQE	ubiquitination	[1]
261	LKWTFNEKSVIKSVH	ubiquitination	[1]

Reference

 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 

Functional Description

 Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. 

Sequence Annotation

 CARBOHYD 60 60 N-linked (GlcNAc...) (Potential).
 CARBOHYD 332 332 N-linked (GlcNAc...) (Potential).  

Keyword

 Complete proteome; Endoplasmic reticulum; Glycoprotein; Glycosyltransferase; Membrane; Reference proteome; Signal; Transferase; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 430 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005635; C:nuclear envelope; IDA:SGD.
 GO:0008250; C:oligosaccharyltransferase complex; IPI:SGD.
 GO:0004579; F:dolichyl-diphosphooligosaccharide-protein glycotransferase activity; IPI:SGD.
 GO:0006487; P:protein N-linked glycosylation; IPI:SGD.
 GO:0018279; P:protein N-linked glycosylation via asparagine; IEA:InterPro. 

Interpro

 IPR005013; WBP1. 

Pfam

 PF03345; DDOST_48kD 

SMART

  

PROSITE

  

PRINTS