CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039427
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Lamc1 
Protein Synonyms/Alias
  
Gene Name
 Lamc1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
266DEVFNDPKVLKSYYYacetylation[1]
1189RRLAERHKQEADDIVacetylation[1]
1320RGKEHEVKNLLEKGKacetylation[1]
1352ALAEEAAKKGRNTLQacetylation[1]
1402TIAEANEKTREAQLAacetylation[1]
1421AADATEAKNKAHEAEacetylation[1]
1474EEAENELKRKQDDADacetylation[1]
1591IHNLEDIKKTLPTGCacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Disulfide bond; Laminin EGF-like domain; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1607 AA 
Protein Sequence
MTGGRRAALA LQLQRRLWLL LAVLAAVACW VRAAMDECAD EGGRPQRCMP EFVNAAFNVT 60
VVATNTCGTP PEEYCVQTGV TGVTKSCHLC DAGQLHLQHG AAFLTDYNNQ ADTTWWQSQT 120
MLAGVQYPNS INLTLHLGKA FDITYVRLKF HTSRPESFAI YKRTREDGPW IPYQYYSGSC 180
ENTYSKANRG FIRTGGDEQQ ALCTDEFSDI SPLTGGNVAF STLEGRPSAY NFDNSPVLQE 240
WVTATDIRVT LNRLNTFGDE VFNDPKVLKS YYYAISDFAV GGRCKCNGHA SECVKNEFGK 300
LVCNCKHNTY GVDCEKCLPF FNDRPWRRAT AESANQCLPC DCNGRSQECY FDPELYRSTG 360
HGGHCTNCRD NTDGAKCERC RENFFRLGNT EACSPCHCSP VGSLSTQCDS YGRCSCKPGV 420
MGDKCDRCQP GFHSLTEAGC RPCSCDPSGS TDECNVETGR CVCKDNVEGF SCERCKPGFF 480
NLESSNPKGC TPCFCFGHSS VCTNAVGYSV YDISSTFQID EDGWRVEQRD GSEASLEWSS 540
DRQDIAVISD TYFPRYFVAP AKFLGNQVLS YGQNLSFSFR VDRRDTRLSA EDLVLEGAGL 600
RVSVPLIAQG NSYPSETTVK YIFRLHEATD YPWRPALSPF EFQKLLNNLT SIKIRGTYSE 660
RSAGYLDDVT LQSARPGPGV PATWVESCTC PVGYGGQFCE TCLPGYRRET PSLGPYSPCV 720
LCTCNGHSET CDPETGVCDC RDNTAGPHCE KCSDGYYGDS TLGTSSDCQP CPCPGGSSCA 780
IVPKTKEVVC THCPTGTAGK RCELCDDGYF GDPLGSNGPV RLCRPCQCND NIDPNAVGNC 840
NRLTGECLKC IYNTAGFYCD RCKEGFFGNP LAPNPADKCK ACACNPYGTV QQQSSCNPVT 900
GQCQCLPHVS GRDCGACDPG FYNLQSGQGC ESCDCHALGS TNGQCDIRTG QCECQPGITG 960
QHCERCETNH FGFGPEGCKP CDCHHEGSLS LQCKDDGRCE CREGFVGNRC DQCEENYFYN 1020
RSWPGCQECP ACYRLVKDKV AEHRVKLQEL ESLIANLGTG DETVTDQAFE DRLKEAEREV 1080
TDLLREAQEV KDVDQNLMDR LQRVNNSLHS QISRLHNIRN TIEETGILAE RARSRVESTE 1140
QLIEIASREL EKAKMAAANV SITQPESTGE PNNMTLLAEE ARRLAERHKQ EADDIVRVAK 1200
TANETSAEAY NLLLRTLAGE NQTALEIEEL NRKYEQAKNI SQDLEKQAAR VHEEAKRAGD 1260
KAVEIYASVA QLTPVDSEAL ESEANKIKKE AADLDRLIDQ KLKDYEDLRE DMRGKEHEVK 1320
NLLEKGKAEQ QTADQLLARA DAAKALAEEA AKKGRNTLQE ANDILNNLKD FDRRVNDNKT 1380
AAEEALRRIP AINRTIAEAN EKTREAQLAL GNAAADATEA KNKAHEAERI ASGVQKNATS 1440
TKADAERTFS EVTDLDNEVN GMLRQLEEAE NELKRKQDDA DQDMMMAGMA SQAAQEAELN 1500
ARKAKNSVSS LLSQLTDLLE QLGQLDTVDL NKLNEIEGSL NKAKDEMKVS DLDRKVSNLE 1560
NEARKQEAAI LDYDRDIAEI IKDIHNLEDI KKTLPTGCFN TPSIEKP 1607 
Gene Ontology
 GO:0070062; C:extracellular vesicular exosome; IEA:Compara.
 GO:0005606; C:laminin-1 complex; IDA:RGD.
 GO:0043259; C:laminin-10 complex; IEA:Compara.
 GO:0005201; F:extracellular matrix structural constituent; IEA:Compara.
 GO:0043208; F:glycosphingolipid binding; IEA:Compara.
 GO:0016477; P:cell migration; IEA:Compara.
 GO:0022617; P:extracellular matrix disassembly; IEA:Compara.
 GO:0031581; P:hemidesmosome assembly; IEA:Compara.
 GO:0031175; P:neuron projection development; IEA:Compara.
 GO:0006461; P:protein complex assembly; IEA:Compara.
 GO:0034446; P:substrate adhesion-dependent cell spreading; IEA:Compara. 
Interpro
 IPR013032; EGF-like_CS.
 IPR002049; EGF_laminin.
 IPR008979; Galactose-bd-like.
 IPR018031; Laminin_B_subgr.
 IPR000034; Laminin_B_type_IV.
 IPR008211; Laminin_N. 
Pfam
 PF00052; Laminin_B
 PF00053; Laminin_EGF
 PF00055; Laminin_N 
SMART
 SM00180; EGF_Lam
 SM00281; LamB
 SM00136; LamNT 
PROSITE
 PS00022; EGF_1
 PS01248; EGF_LAM_1
 PS50027; EGF_LAM_2
 PS51115; LAMININ_IVA
 PS51117; LAMININ_NTER 
PRINTS