| Tag | Content |
|---|
| CPLM ID | CPLM-008639 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | tRNA(His) guanylyltransferase |
Protein Synonyms/Alias | tRNA-histidine guanylyltransferase |
Gene Name | THG1 |
Gene Synonyms/Alias | YGR024C |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 5 | ***MANSKFGYVRQF | acetylation | [1] | | 125 | PEKPLNIKHLPYFDS | acetylation | [1] |
|
Reference | [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [ PMID: 22865919] |
Functional Description | Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. |
Sequence Annotation | NP_BIND 29 34 GTP (By similarity).
NP_BIND 76 77 GTP (By similarity).
METAL 29 29 Magnesium 1; catalytic (By similarity).
METAL 29 29 Magnesium 2; catalytic (By similarity).
METAL 30 30 Magnesium 1; via carbonyl oxygen;
METAL 77 77 Magnesium 1; catalytic (By similarity).
METAL 77 77 Magnesium 2; catalytic (By similarity). |
Keyword | Complete proteome; GTP-binding; Magnesium; Metal-binding; Nucleotide-binding; Nucleotidyltransferase; Reference proteome; Transferase; tRNA processing. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 237 AA |
Protein Sequence | MANSKFGYVR QFETHDVILP QCYIVVRIDG KKFHEFSKFY EFAKPNDENA LKLMNACAKN 60
LVLKYKNDII LAFGESDEYS FILKSSTTLF NRRKDKLATL FGSFFTSNYV ALWAKFFPEK 120
PLNIKHLPYF DSRCVAYPNL QTIKDYLSWR YVDTHINNLY NTTFWQLIIK CGLTPQESEK 180
KLCGTFSNEK QEILFSECGI NYNNEPEMFK KGSLVTRKGE ILHINVIAQI DELFEGY 237 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |