CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-000830
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Probable G-protein coupled receptor 27 
Protein Synonyms/Alias
 Super conserved receptor expressed in brain 1 
Gene Name
 Gpr27 
Gene Synonyms/Alias
 Sreb1 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
281LLVLEEFKTEKRLCKubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Orphan receptor. Possible candidate for amine-like G- protein coupled receptor (By similarity). 
Sequence Annotation
 CARBOHYD 3 3 N-linked (GlcNAc...) (Potential).
 DISULFID 98 175 By similarity.  
Keyword
 Cell membrane; Complete proteome; Disulfide bond; G-protein coupled receptor; Glycoprotein; Membrane; Receptor; Reference proteome; Transducer; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 379 AA 
Protein Sequence
MANASEPGGG GSGGGAEAAA LGLRLATLSL LLCVSLAGNV LFALLIVRER SLHRAPYYLL 60
LDLCLADGLR ALACLPAVML AARRAAAAAG TPPGALGCKL LAFLAALFCF HAAFLLLGVG 120
VTRYLAIAHH RFYAERLAGW PCAAMLVCAA WALALAAAFP PVLDGGGADD EDAPCALEQR 180
PDGAPGALGF LLLLAAVVGA THLVYLRLLF FIHDRRKMRP ARLVPAVSHD WTFHGPGATG 240
QAAANWTAGF GRGPTPPALV GIRPAGPGRG ARRLLVLEEF KTEKRLCKMF YAITLLFLLL 300
WGPYVVASYL RVLVRPGAVP QAYLTASVWL TFAQAGINPV VCFLFNRELR DCFRAQFPCC 360
QSPQATQATL PCDLKGIGL 379 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0004930; F:G-protein coupled receptor activity; IEA:UniProtKB-KW. 
Interpro
 IPR000276; GPCR_Rhodpsn.
 IPR017452; GPCR_Rhodpsn_7TM. 
Pfam
 PF00001; 7tm_1 
SMART
  
PROSITE
 PS00237; G_PROTEIN_RECEP_F1_1
 PS50262; G_PROTEIN_RECEP_F1_2 
PRINTS
 PR00237; GPCRRHODOPSN.