UniProt Accession

 HIS8_YEAST; P07172; D6VVH1 

Genbank Protein ID

 Z38125; X05650; M38613; BK006942 

Genbank Nucleotide ID

 CAA86264.1; CAA29139.1; AAA34675.1; DAA08437.1 

Protein Name

 Histidinol-phosphate aminotransferase 

Protein Synonyms/Alias

 Imidazole acetol-phosphate transaminase 

Gene Name

 HIS5 

Gene Synonyms/Alias

 YIL116W 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
292	SKIINEEKMRLLKEL	ubiquitination	[1]
331	GGDNVLAKKLYYQLA	ubiquitination	[1]
373	EENTHLIKYFKETLY	acetylation	[2]

Reference

 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [2] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 

Functional Description

  

Sequence Annotation

 MOD_RES 230 230 N6-(pyridoxal phosphate)lysine  

Keyword

 Amino-acid biosynthesis; Aminotransferase; Complete proteome; Histidine biosynthesis; Pyridoxal phosphate; Reference proteome; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 385 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:SGD.
 GO:0004400; F:histidinol-phosphate transaminase activity; IMP:SGD.
 GO:0080130; F:L-phenylalanine:2-oxoglutarate aminotransferase activity; IEA:EC.
 GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
 GO:0000105; P:histidine biosynthetic process; IMP:SGD. 

Interpro

 IPR001917; Aminotrans_II_pyridoxalP_BS.
 IPR004839; Aminotransferase_I/II.
 IPR005861; HisP_aminotrans.
 IPR015424; PyrdxlP-dep_Trfase.
 IPR015421; PyrdxlP-dep_Trfase_major_sub1.
 IPR015422; PyrdxlP-dep_Trfase_major_sub2. 

Pfam

 PF00155; Aminotran_1_2 

SMART

  

PROSITE

 PS00599; AA_TRANSFER_CLASS_2 

PRINTS