CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040871
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Anaphase-promoting complex subunit 1 
Protein Synonyms/Alias
  
Gene Name
 ANAPC1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
29PFGRDHCKHHPNALNubiquitination[1]
69QEVTIHEKQKESWQLubiquitination[2, 3]
71VTIHEKQKESWQLRKubiquitination[1]
107VIWSKGSKSQALAVYubiquitination[1]
137DFIISQDKSEKAYSCubiquitination[3]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 149 AA 
Protein Sequence
MSNFYEERTT MIAARDLQEF VPFGRDHCKH HPNALNLQLR QLQPASELWS SDGAAGLVGS 60
LQEVTIHEKQ KESWQLRKGV SEIGEDVDYD EELYVAGNMV IWSKGSKSQA LAVYKAFTVD 120
SPVQQALWCD FIISQDKSEK AYSCKCLAH 149 
Gene Ontology
 GO:0005680; C:anaphase-promoting complex; IEA:InterPro. 
Interpro
 IPR024990; Apc1. 
Pfam
  
SMART
  
PROSITE
  
PRINTS