CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-005421
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 KRR1 small subunit processome component 
Protein Synonyms/Alias
 KRR-R motif-containing protein 1; Ribosomal RNA assembly protein KRR1 
Gene Name
 KRR1 
Gene Synonyms/Alias
 YCL059C; YCL59C 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
18WDTDDIDKWKIEEFKacetylation[1]
102LKARDLIKLLARSVPacetylation[1]
Reference
 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919
Functional Description
 Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. Essential for vegetative growth. 
Sequence Annotation
 DOMAIN 122 192 KH.  
Keyword
 Complete proteome; Nucleus; Reference proteome; Ribonucleoprotein; Ribosome biogenesis; RNA-binding; rRNA processing. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 316 AA 
Protein Sequence
MVSTHNRDKP WDTDDIDKWK IEEFKEEDNA SGQPFAEESS FMTLFPKYRE SYLKTIWNDV 60
TRALDKHNIA CVLDLVEGSM TVKTTRKTYD PAIILKARDL IKLLARSVPF PQAVKILQDD 120
MACDVIKIGN FVTNKERFVK RRQRLVGPNG NTLKALELLT KCYILVQGNT VSAMGPFKGL 180
KEVRRVVEDC MKNIHPIYHI KELMIKRELA KRPELANEDW SRFLPMFKKR NVARKKPKKI 240
RNVEKKVYTP FPPAQLPRKV DLEIESGEYF LSKREKQMKK LNEQKEKQME REIERQEERA 300
KDFIAPEEEA YKPNQN 316 
Gene Ontology
 GO:0030686; C:90S preribosome; IDA:SGD.
 GO:0005730; C:nucleolus; IDA:SGD.
 GO:0032040; C:small-subunit processome; IDA:SGD.
 GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
 GO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD. 
Interpro
 IPR004087; KH_dom.
 IPR024166; rRNA_assembly_KRR1. 
Pfam
  
SMART
 SM00322; KH 
PROSITE
 PS50084; KH_TYPE_1 
PRINTS