CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013305
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Centrosomal protein of 41 kDa 
Protein Synonyms/Alias
 Cep41; Testis-specific gene A14 protein 
Gene Name
 Cep41 
Gene Synonyms/Alias
 Tsga14 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
336NSGHLQGKPWK****acetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405
Functional Description
 Required during ciliogenesis for tubulin glutamylation in cilium. Probably acts by participating in the transport of TTLL6, a tubulin polyglutamylase, between the basal body and the cilium (By similarity). 
Sequence Annotation
 DOMAIN 135 232 Rhodanese.
 MOD_RES 65 65 Phosphoserine (By similarity).  
Keyword
 Cell projection; Ciliopathy; Cilium; Cilium biogenesis/degradation; Complete proteome; Cytoplasm; Cytoskeleton; Phosphoprotein; Protein transport; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 339 AA 
Protein Sequence
MSDSPIDGSP QPEPDYRYKK DELFKRIKVT TFAQLVIQVA SLSDQTLEVT AEEIQRLEDS 60
DSATSEADTD IAAKTNGKGS PEEQSPSPVQ FINSTGAGDA SRSTLQSVIS GVGELDVDKG 120
LVKKEEPSGK DKPYPDCPFL LLDVRDRDSY QQCHIVGAYS YPIATLSRTM NPYSNDILEY 180
KNAHGKIIIL YDDDERLASQ AATTMCERGF ENLFMLSGGL KVLAQKFPEG LVTGSLPASC 240
QQALPFGSVR KRPGPKMPAL PAENKWRFTP EDLKKIECYL EADQGPANNP SRLNQNNSAG 300
RDLKVPAGRG GQNLPTGCPT SHSNSRTLNS GHLQGKPWK 339 
Gene Ontology
 GO:0005814; C:centriole; ISS:UniProtKB.
 GO:0036064; C:cilium basal body; ISS:UniProtKB.
 GO:0072372; C:primary cilium; ISS:UniProtKB.
 GO:0042384; P:cilium assembly; ISS:UniProtKB.
 GO:0018095; P:protein polyglutamylation; ISS:UniProtKB.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW. 
Interpro
 IPR001763; Rhodanese-like_dom. 
Pfam
 PF00581; Rhodanese 
SMART
 SM00450; RHOD 
PROSITE
 PS50206; RHODANESE_3 
PRINTS