CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040324
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Calcium uptake protein 1, mitochondrial 
Protein Synonyms/Alias
  
Gene Name
 MICU1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
110RSGFRDRKVMEYENRubiquitination[1, 2]
126RAYSTPDKIFRYFATubiquitination[1]
161RSITPNEKQPEHLGLubiquitination[1]
174GLDQYIIKRFDGKNKubiquitination[1]
296LKGKLTIKNFLEFQRubiquitination[1]
451MRGLEKPKDMGFTRLubiquitination[1, 2]
477AWDFALPKQ******ubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Calcium; Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 478 AA 
Protein Sequence
MFRLNSLSAL AELAVGSRWY HGGSQPIQIR RRLMMVAFLG ASAVTASTGL LWKRAHAESP 60
PCVDNLKSDI GDKGKNKDEG DVCNHEKKTA DLAPHPEEKK KKRSGFRDRK VMEYENRIRA 120
YSTPDKIFRY FATLKVISEP GEAEVFMTPE DFVRSITPNE KQPEHLGLDQ YIIKRFDGKN 180
KKISQEREKF ADEGSIFYTL GECGLISFSD YIFLTTVLST PQRNFEIAFK MFDLNGDGEV 240
DMEEFEQAIS IIRSQTSMGM RHRDRPTTGN TLKSGLCSAL TTYFFGADLK GKLTIKNFLE 300
FQRKLQHDVL KLEFERHDPV DGRITERQFG GMLLAYSGVQ SKKLTAMQRQ LKKHFKEGKG 360
LTFQEVENFF TFLKNINDVD TALSFYHMAG ASLDKVTMQQ VARTVAKVEL SDHVCDVVFA 420
LFDCDGNGEL SNKEFVSIMK QRLMRGLEKP KDMGFTRLMQ AMWKCAQETA WDFALPKQ 478 
Gene Ontology
 GO:0005509; F:calcium ion binding; IEA:InterPro. 
Interpro
 IPR011992; EF-hand-like_dom.
 IPR018247; EF_Hand_1_Ca_BS.
 IPR002048; EF_hand_dom. 
Pfam
 PF13202; EF_hand_3 
SMART
 SM00054; EFh 
PROSITE
 PS00018; EF_HAND_1
 PS50222; EF_HAND_2 
PRINTS