CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-012921
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Serine palmitoyltransferase-regulating protein TSC3 
Protein Synonyms/Alias
 Temperature-sensitive CSG2-mutant suppressor protein 3 
Gene Name
 TSC3 
Gene Synonyms/Alias
 YBR058C-A 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
15MVYIPTTKEAKRRNGubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301
Functional Description
 Stimulates the activity of serine palmitoyltransferase (SPT). 
Sequence Annotation
  
Keyword
 Complete proteome; Endoplasmic reticulum; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 80 AA 
Protein Sequence
MTQHKSSMVY IPTTKEAKRR NGKSEGILNT IEEVVEKLYW TYYIHLPFYL MASFDSFFLH 60
VFFLTIFSLS FFGILKYCFL 80 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0035339; C:SPOTS complex; IDA:UniProtKB.
 GO:0008047; F:enzyme activator activity; IDA:SGD.
 GO:0006666; P:3-keto-sphinganine metabolic process; IPI:SGD.
 GO:0030148; P:sphingolipid biosynthetic process; TAS:SGD. 
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS