| Tag | Content |
|---|
| CPLM ID | CPLM-019865 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Aminoacylase-1 |
Protein Synonyms/Alias | ACY-1; N-acyl-L-amino-acid amidohydrolase |
Gene Name | Acy1 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 4 | ****MTTKDPESEHP | ubiquitination | [1] | | 284 | VAPDVDMKAFEKQLQ | ubiquitination | [1] | | 288 | VDMKAFEKQLQRWCQ | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Involved in the hydrolysis of N-acylated or N-acetylated amino acids (except L-aspartate) (By similarity). |
Sequence Annotation | ACT_SITE 82 82 By similarity.
ACT_SITE 147 147 Proton acceptor (By similarity).
METAL 80 80 Zinc 1 (By similarity).
METAL 113 113 Zinc 1 (By similarity).
METAL 113 113 Zinc 2 (By similarity).
METAL 148 148 Zinc 2 (By similarity).
METAL 175 175 Zinc 1 (By similarity).
METAL 373 373 Zinc 2 (By similarity). |
Keyword | Complete proteome; Cytoplasm; Hydrolase; Metal-binding; Reference proteome; Zinc. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 408 AA |
Protein Sequence | MTTKDPESEH PSVTLFRQYL RICTVQPNPD YGGAITFLEE RARQLGLSCQ KIEVVPGFVI 60
TVLTWPGTNP SLPSILLNSH TDVVPVFKEH WHHDPFEAFK DSEGYIYARG SQDMKSVSIQ 120
YLEAVRRLKS EGHRFPRTIH MTFVPDEEVG GHKGMELFVK RPEFQALRAG FALDEGLANP 180
TDAFTVFYSE RSPWWVRVTS TGKPGHASRF IEDTAAEKLH KVISSILAFR EKERQRLQAN 240
PHLKEGAVTS VNLTKLEGGV AYNVVPATMS ASFDFRVAPD VDMKAFEKQL QRWCQEAGEG 300
VTFEFAQKFT EPRMTPTDDS DPWWAAFSGA CKAMNLTLEP EIFPAATDSR YIRAVGIPAL 360
GFSPMNRTPV LLHDHNERLH EDIFLRGVDI YTGLLSALAS VPTLPGES 408 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0004046; F:aminoacylase activity; IEA:EC. GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. GO:0008237; F:metallopeptidase activity; IEA:InterPro. GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro. GO:0006508; P:proteolysis; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |