UniProt Accession

 H0Y2X5_HUMAN; H0Y2X5 

Genbank Protein ID

 AC015712; CH471101 

Genbank Nucleotide ID

 EAX02283.1 

Protein Name

 Aldehyde dehydrogenase 1 family, member A3, isoform CRA_b 

Protein Synonyms/Alias

 Aldehyde dehydrogenase family 1 member A3 

Gene Name

 ALDH1A3 

Gene Synonyms/Alias

 hCG_28035 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
33	NLEVKFTKIFINNEW	ubiquitination	[1]
44	NNEWHESKSGKKFAT	ubiquitination	[2]
156	TGSTEVGKLVKEAAS	ubiquitination	[1, 2]
159	TEVGKLVKEAASRSN	ubiquitination	[1]
233	RSVEYAKKRPVGDPF	ubiquitination	[1, 2, 3]
243	VGDPFDVKTEQGPQI	ubiquitination	[1, 2, 3]
253	QGPQIDQKQFDKILE	ubiquitination	[1, 2, 3]
266	LELIESGKKEGAKLE	ubiquitination	[1, 2]
287	EDKGLFIKPTVFSEV	ubiquitination	[1, 2, 3]
302	TDNMRIAKEEIFGPV	ubiquitination	[1, 2, 3]
314	GPVQPILKFKSIEEV	ubiquitination	[1, 2]
316	VQPILKFKSIEEVIK	ubiquitination	[1, 2]
323	KSIEEVIKRANSTDY	ubiquitination	[1, 2]
339	LTAAVFTKNLDKALK	ubiquitination	[1, 2]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [3] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Oxidoreductase; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 405 AA 

Protein Sequence

Gene Ontology

 GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro. 

Interpro

 IPR016161; Ald_DH/histidinol_DH.
 IPR016163; Ald_DH_C.
 IPR016160; Ald_DH_CS.
 IPR016162; Ald_DH_N.
 IPR015590; Aldehyde_DH_dom. 

Pfam

 PF00171; Aldedh 

SMART

  

PROSITE

 PS00070; ALDEHYDE_DEHYDR_CYS
 PS00687; ALDEHYDE_DEHYDR_GLU 

PRINTS