UniProt Accession

 HLF_HUMAN; Q16534 

Genbank Protein ID

 M95585; M95586; X68985; BC036093 

Genbank Nucleotide ID

 AAA52675.1; AAA58445.1; CAA48777.1; AAH36093.1 

Protein Name

 Hepatic leukemia factor 

Protein Synonyms/Alias

  

Gene Name

 HLF 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
3	*****MEKMSRPLPL	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

 DOMAIN 225 288 bZIP.
 REGION 227 247 Basic motif (By similarity).
 REGION 248 255 Leucine-zipper (By similarity).  

Keyword

 Biological rhythms; Chromosomal rearrangement; Complete proteome; DNA-binding; Nucleus; Proto-oncogene; Reference proteome; Transcription; Transcription regulation. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 295 AA 

Protein Sequence

Gene Ontology

 GO:0005634; C:nucleus; TAS:ProtInc.
 GO:0003690; F:double-stranded DNA binding; TAS:ProtInc.
 GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
 GO:0007275; P:multicellular organismal development; TAS:ProtInc.
 GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.
 GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc. 

Interpro

 IPR004827; bZIP. 

Pfam

 PF07716; bZIP_2 

SMART

 SM00338; BRLZ 

PROSITE

 PS50217; BZIP
 PS00036; BZIP_BASIC 

PRINTS