| Tag | Content |
|---|
| CPLM ID | CPLM-020567 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | 26S proteasome non-ATPase regulatory subunit 9 |
Protein Synonyms/Alias | 26S proteasome regulatory subunit p27 |
Gene Name | Psmd9 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 91 | NDHKALMKQVEEALH | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the PA700/19S regulatory complex (RC). During the base subcomplex assembly is part of an intermediate PSMD9:PSMC6:PSMC3 module, also known as modulator trimer complex; PSMD9 is released during the further base assembly process (By similarity). |
Sequence Annotation | DOMAIN 108 194 PDZ.
MOD_RES 128 128 Phosphoserine. |
Keyword | Chaperone; Complete proteome; Phosphoprotein; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 222 AA |
Protein Sequence | MSGEDVPHRA ESSEARAAAV SDIQDLMRRK EEIEAEIKAN YDVLESQKGI GMNEPLVDCE 60
GYPRADVDLY QVRTARHNII CLQNDHKALM KQVEEALHQL HARDKEKQAR DMAEAREEAM 120
NRRLASNSPV LPQAFARVNS ISPGSPASIA GLQVDDEIVE FGSVNTQNFQ SVQNVGTVVQ 180
HSEGKPLNVT VIRRGEKHQL RLIPTRWAGK GLLGCNIIPL QR 222 |
Gene Ontology | GO:0005634; C:nucleus; ISS:BHF-UCL. GO:0043425; F:bHLH transcription factor binding; ISS:BHF-UCL. GO:0003713; F:transcription coactivator activity; ISS:BHF-UCL. GO:0046676; P:negative regulation of insulin secretion; ISS:BHF-UCL. GO:0032024; P:positive regulation of insulin secretion; ISS:BHF-UCL. GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:BHF-UCL. GO:0070682; P:proteasome regulatory particle assembly; ISS:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |