CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011447
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 UBX domain-containing protein 5 
Protein Synonyms/Alias
  
Gene Name
 UBX5 
Gene Synonyms/Alias
 YDR330W 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
228KLDLDAAKQKARAKQubiquitination[1]
353TVNEPLPKVDPTTLTubiquitination[1]
379SLNNNSSKSNQEEVPubiquitination[1, 2]
393PSTGEEQKRVQEPDPubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [2] Sites of ubiquitin attachment in Saccharomyces cerevisiae.
 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.
 Proteomics. 2012 Jan;12(2):236-40. [PMID: 22106047] 
Functional Description
 Involved in CDC48-dependent protein degradation through the ubiquitin/proteasome pathway (By similarity). 
Sequence Annotation
 DOMAIN 415 493 UBX.
 MOD_RES 139 139 Phosphoserine.  
Keyword
 Complete proteome; Cytoplasm; Nucleus; Phosphoprotein; Reference proteome; Ubl conjugation pathway. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 500 AA 
Protein Sequence
MSEGKVDEFM AITGADDAAI ATQFIEMADG NLNTAISLFF ENGGAALLSS NNTPTPSNST 60
PMAPTSVDSD ADAQLAERLQ REAYQQQQPD QDYVRPPDEA RHEVLTETSG FPISYGGIGG 120
RFEPLHRVND MFDEGRPESI FNQRLDDTNT NTYINDNSSD SLDSEEENDD DEYEYVEEPV 180
IELDEDGNIK EYTKLVRKPK TISKEQKLAL LFRPPFSIMS KLDLDAAKQK ARAKQKWIMI 240
NIQDSGIFQC QALNRDLWSS RPVKTIIKEN FVFLQYQYES RNAQPYLQFY HLNNKDDLPH 300
IAILDPITGE RVKQWNRVVP IPEQFISEIN EFLASFSLDP KVPNPTVNEP LPKVDPTTLT 360
EEQQMELAIK ESLNNNSSKS NQEEVPSTGE EQKRVQEPDP FSTIEARVHP EPPNKPGITT 420
RIQIRTGDGS RLVRRFNALE DTVRTIYEVI KTEMDGFADS RFTLNDHQRE DLIDKLNMTI 480
ADAGLKNSSL LLEKLDPEIE 500 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:SGD.
 GO:0005634; C:nucleus; IDA:SGD.
 GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IMP:SGD. 
Interpro
 IPR012336; Thioredoxin-like_fold.
 IPR009060; UBA-like.
 IPR001012; UBX. 
Pfam
 PF00789; UBX 
SMART
 SM00166; UBX 
PROSITE
 PS50033; UBX 
PRINTS