CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-005924
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Uncharacterized HTH-type transcriptional regulator YafC 
Protein Synonyms/Alias
  
Gene Name
 yafC 
Gene Synonyms/Alias
 b0208; JW0198 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
113HFLMPLIKPFRERYPacetylation[1]
178DYISRYGKPETIDDLacetylation[1]
186PETIDDLKQHICLGFacetylation[1]
215DGQLHEVKYGLSSNSacetylation[1]
294DFLSEHVKTAPGGAVacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 
Functional Description
  
Sequence Annotation
 DOMAIN 1 60 HTH lysR-type.
 DNA_BIND 20 39 H-T-H motif (By similarity).  
Keyword
 Complete proteome; DNA-binding; Reference proteome; Transcription; Transcription regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 304 AA 
Protein Sequence
MKATSEELAI FVSVVESGSF SRAAEQLGQA NSAVSRAVKK LEMKLGVSLL NRTTRQLSLT 60
EEGERYFRRV QSILQEMAAA ESEIMETRNT PRGLLRIDAA TPVVLHFLMP LIKPFRERYP 120
EVTLSLVSSE TIINLIERKV DVAIRAGTLT DSSLRARPLF NSYRKIIASP DYISRYGKPE 180
TIDDLKQHIC LGFTEPASLN TWPIARSDGQ LHEVKYGLSS NSGETLKQLC LSGNGIACLS 240
DYMIDKEIAR GELVELMADK VLPVEMPFSA VYYSDRAVST RIRAFIDFLS EHVKTAPGGA 300
VREA 304 
Gene Ontology
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR005119; LysR_subst-bd.
 IPR000847; Tscrpt_reg_HTH_LysR.
 IPR011991; WHTH_DNA-bd_dom. 
Pfam
 PF00126; HTH_1
 PF03466; LysR_substrate 
SMART
  
PROSITE
 PS50931; HTH_LYSR 
PRINTS
 PR00039; HTHLYSR.