CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030289
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Leucine rich repeat containing 8 family, member B 
Protein Synonyms/Alias
 Leucine-rich repeat-containing protein 8B 
Gene Name
 Lrrc8b 
Gene Synonyms/Alias
 mCG_52435 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
182EQSVRPLKLSKSKTLubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Leucine-rich repeat; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 803 AA 
Protein Sequence
MITLTELKCL ADAQSSYHIL KPWWDVFWYY ITLIMLLVAV LAGALQLTQS RVLCCLPCKV 60
EFDNQCAVPW DLLKGSENAS SNSGLLLPLP LRIQNDLHRQ QYSYIDAVCY EKQLHWFAKF 120
FPYLVLLHTL IFAACSNFWL HYPSTSSRLE HFVSILHKCF DSPWTTRALS ETVAEQSVRP 180
LKLSKSKTLL STSGGSADID ASKQSLPYPQ PGLESPGIES PTSSVLDKKE GEQAKAIFEK 240
VKRFRLHVEQ RDIIYRVYLK QIIVKVILFV LIITYVPYFL SYITLEIDCS IDVQAFTGYK 300
RYQCVYSLAE IFKVLASFYV ILVMLYGLTS SYSLWWMLRS SLKQYSFEAL REKSNYSDIP 360
DVKNDFAFIL HLADQYDPLY SKRFSIFLSE VSENKLKQIN LNNEWTVERL KSKLVKNSQD 420
KVELHLFMLN GLPDNVFELT EMEVLSLELI PEVKLPAAVA QLVNLRELHV YHSSLVVDHP 480
ALAFLEENLR ILRLKFTEMG KIPRWVFHLK NLKELYLSGC VLPEQLSSLH LEGFQDLKNL 540
RTLYLKSSLS RIPQVVTDLL PSLQKLSLDN EGSKLVVLNN LKKMVNLKSL ELLSCDLERI 600
PHSIFSLNNL HELDLKENNL KTVEEIISFQ HLPSLSCLKL WHNNIAYIPA QIGALSNLEQ 660
LFLGHNNIES LPLQLFLCTK LHYLDLSYNH LTFIPEEIQY LTNLQYFAVT NNNIEMLPDG 720
LFQCKKLQCL LLGRNSLTDL SPLVGELSNL THLELTGNYL ETLPVELEGC QSLKRSCLIV 780
EDSLLNSLPL PVAERLQTCL DKC 803 
Gene Ontology
  
Interpro
 IPR001611; Leu-rich_rpt.
 IPR003591; Leu-rich_rpt_typical-subtyp.
 IPR021040; LRR_protein-8_N. 
Pfam
 PF12534; DUF3733
 PF00560; LRR_1 
SMART
 SM00369; LRR_TYP 
PROSITE
 PS51450; LRR 
PRINTS