| Tag | Content |
|---|
| CPLM ID | CPLM-011303 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Ribonuclease H2 subunit B |
Protein Synonyms/Alias | RNase H2 subunit B; Rnh2B; RNase H(202); Ribonuclease HI subunit B |
Gene Name | RNH202 |
Gene Synonyms/Alias | YDR279W |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 62 | IRSFQFGKGPSYSHE | acetylation | [1] | | 340 | KPKVAIGKGAIDGFF | acetylation | [1] |
|
Reference | [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [ PMID: 22865919] |
Functional Description | Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging- strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. |
Sequence Annotation | |
Keyword | Complete proteome; Direct protein sequencing; Nucleus; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 350 AA |
Protein Sequence | MTVSNIGGEE RLIILPDDYE TSKTINTFTL PPPSNITSKP RIELFENING KLYEIRSFQF 60
GKGPSYSHEE DLANDKYHYT KENHPIKSTF IVNTSDPTDG YVFNSSKIHF CSLYDIAFSL 120
IGFYYRNSVS ADEQDYSNSS DTGENQKSNS KTNEKFLTVR DYHDFLTDNH DKNWENISLS 180
RLKSGLAKVS ETIEEAGDVY YKITSAMITQ FLLGKVSKIV ENFPPSIPTL KNAPTEIKQC 240
YKVVMATNLL VSLIPRAAYH NLLTFSPTMD SGCLNPDIKA SFIELENYET TNELQNAERE 300
LLMKSAMNVG LNSNGRVSLP VKKVTKKIVQ NKKPKVAIGK GAIDGFFKRK 350 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |