CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042002
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 TCDD-inducible poly [ADP-ribose] polymerase 
Protein Synonyms/Alias
 TCDD-inducible poly(ADP-ribose) polymerase, isoform CRA_b 
Gene Name
 TIPARP 
Gene Synonyms/Alias
 hCG_27716 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
544DVVDGICKHNFDPRVubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 654 AA 
Protein Sequence
MEMETTEPEP DCVVQPPSPP DDFSCQMRLS EKITPLKTCF KKKDQKRLGT GTLRSLRPIL 60
NTLLESGSLD GVFRSRNQST DENSLHEPMM KKAMEINSSC PPAENNMSVL IPDRTNVGDQ 120
IPEAHPSTEA PERVVPIQDH SFPSETLSGT VADSTPAHFQ TDLLHPVSSD VPTSPDCLDK 180
VIDYVPGIFQ ENSFTIQYIL DTSDKLSTEL FQDKSEEASL DLVFELVNQL QYHTHQENGI 240
EICMDFLQGT CIYGRDCLKH HTVLPYHWQI KRTTTQKWQS VFNDSQEHLE RFYCNPENDR 300
MRMKYGGQEF WADLNAMNVY ETTEFDQLRR LSTPPSSNVN SIYHTVWKFF CRDHFGWREY 360
PESVIRLIEE ANSRGLKEVR FMMWNNHYIL HNSFFRREIK RRPLFRSCFI LLPYLQTLGG 420
VPTQAPPPLE ATSSSQIICP DGVTSANFYP ETWVYMHPSQ DFIQVPVSAE DKSYRIIYNL 480
FHKTVPEFKY RILQILRVQN QFLWEKYKRK KEYMNRKMFG RDRIINERHL FHGTSQDVVD 540
GICKHNFDPR VCGKHATMFG QGSYFAKKAS YSHNFSKKSS KGVHFMFLAK VLTGRYTMGS 600
HGMRRPPPVN PGSVTSDLYD SCVDNFFEPQ IFVIFNDDQS YPYFVIQYEE VSNT 654 
Gene Ontology
 GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IEA:InterPro.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0008209; P:androgen metabolic process; IEA:Compara.
 GO:0008210; P:estrogen metabolic process; IEA:Compara.
 GO:0060325; P:face morphogenesis; IEA:Compara.
 GO:0008585; P:female gonad development; IEA:Compara.
 GO:0030097; P:hemopoiesis; IEA:Compara.
 GO:0001822; P:kidney development; IEA:Compara.
 GO:0044236; P:multicellular organismal metabolic process; IEA:Compara.
 GO:0006807; P:nitrogen compound metabolic process; IEA:Compara.
 GO:0060021; P:palate development; IEA:Compara.
 GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IEA:Compara.
 GO:0009791; P:post-embryonic development; IEA:Compara.
 GO:0006471; P:protein ADP-ribosylation; IEA:Compara.
 GO:0048705; P:skeletal system morphogenesis; IEA:Compara.
 GO:0048745; P:smooth muscle tissue development; IEA:Compara.
 GO:0001570; P:vasculogenesis; IEA:Compara. 
Interpro
 IPR012317; Poly(ADP-ribose)pol_cat_dom.
 IPR004170; WWE-dom.
 IPR000571; Znf_CCCH. 
Pfam
 PF00644; PARP 
SMART
  
PROSITE
 PS51059; PARP_CATALYTIC
 PS50918; WWE
 PS50103; ZF_C3H1 
PRINTS