UniProt Accession

 CHCH6_HUMAN; Q9BRQ6; D6R9U0; D6RIB4; H8Y0Y7 

Genbank Protein ID

 JF264889; AC078867; AC092898; AC117450; CH471052; BC006123 

Genbank Nucleotide ID

 AEA95848.1; EAW79352.1; AAH06123.1 

Protein Name

 Coiled-coil-helix-coiled-coil-helix domain-containing protein 6, mitochondrial 

Protein Synonyms/Alias

 Coiled coil helix cristae morphology protein 1 

Gene Name

 CHCHD6 

Gene Synonyms/Alias

 CHCM1 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
156	RRRDTFYKEQLERIE	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

 Required for maintaining mitochondrial crista morphology, ATP production and oxygen consumption. 

Sequence Annotation

 DOMAIN 190 231 CHCH.
 LIPID 2 2 N-myristoyl glycine (Potential).
 DISULFID 197 228 By similarity.
 DISULFID 207 218 By similarity.  

Keyword

 Coiled coil; Complete proteome; Disulfide bond; Lipoprotein; Membrane; Mitochondrion; Mitochondrion inner membrane; Myristate; Polymorphism; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 235 AA 

Protein Sequence

Gene Ontology

 GO:0005743; C:mitochondrial inner membrane; IDA:UniProtKB.
 GO:0042407; P:cristae formation; IMP:UniProtKB.
 GO:0006974; P:response to DNA damage stimulus; IDA:UniProtKB. 

Interpro

 IPR007964; DUF737. 

Pfam

 PF05300; DUF737 

SMART

  

PROSITE

  

PRINTS