CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017915
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Potassium voltage-gated channel subfamily G member 3 
Protein Synonyms/Alias
 Voltage-gated potassium channel subunit Kv10.1; Voltage-gated potassium channel subunit Kv6.3 
Gene Name
 KCNG3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
28SLSRELLKDFPLRRVubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
 Potassium channel subunit. Modulates channel activity. 
Sequence Annotation
 MOTIF 373 378 Selectivity filter (By similarity).  
Keyword
 Alternative splicing; Cell membrane; Complete proteome; Ion channel; Ion transport; Membrane; Potassium; Potassium channel; Potassium transport; Reference proteome; Transmembrane; Transmembrane helix; Transport; Voltage-gated channel. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 436 AA 
Protein Sequence
MTFGRSGAAS VVLNVGGARY SLSRELLKDF PLRRVSRLHG CRSERDVLEV CDDYDRERNE 60
YFFDRHSEAF GFILLYVRGH GKLRFAPRMC ELSFYNEMIY WGLEGAHLEY CCQRRLDDRM 120
SDTYTFYSAD EPGVLGRDEA RPGGAEAAPS RRWLERMRRT FEEPTSSLAA QILASVSVVF 180
VIVSMVVLCA STLPDWRNAA ADNRSLDDRS RYSAGPGREP SGIIEAICIG WFTAECIVRF 240
IVSKNKCEFV KRPLNIIDLL AITPYYISVL MTVFTGENSQ LQRAGVTLRV LRMMRIFWVI 300
KLARHFIGLQ TLGLTLKRCY REMVMLLVFI CVAMAIFSAL SQLLEHGLDL ETSNKDFTSI 360
PAACWWVIIS MTTVGYGDMY PITVPGRILG GVCVVSGIVL LALPITFIYH SFVQCYHELK 420
FRSARYSRSL STEFLN 436 
Gene Ontology
 GO:0005783; C:endoplasmic reticulum; IDA:UniProtKB.
 GO:0005886; C:plasma membrane; IDA:UniProtKB.
 GO:0008076; C:voltage-gated potassium channel complex; IEA:InterPro.
 GO:0005251; F:delayed rectifier potassium channel activity; IBA:RefGenome.
 GO:0051260; P:protein homooligomerization; IEA:InterPro.
 GO:0007268; P:synaptic transmission; TAS:Reactome. 
Interpro
 IPR000210; BTB/POZ-like.
 IPR011333; BTB/POZ_fold.
 IPR005821; Ion_trans_dom.
 IPR027359; K_channel_four-helix_dom.
 IPR003091; K_chnl.
 IPR003968; K_chnl_volt-dep_Kv.
 IPR003971; K_chnl_volt-dep_Kv9.
 IPR003131; T1-type_BTB. 
Pfam
 PF00520; Ion_trans
 PF02214; K_tetra 
SMART
 SM00225; BTB 
PROSITE
  
PRINTS
 PR00169; KCHANNEL.
 PR01494; KV9CHANNEL.
 PR01491; KVCHANNEL.