UniProt Accession

 BTF3_HUMAN; P20290; A8K510; Q13893; Q76M56 

Genbank Protein ID

 X53280; X53281; M90357; M90352; X74070; AB062126; BT007120; AK291125; CH471084; BC008062 

Genbank Nucleotide ID

 CAA37375.1; CAA37376.1; AAA58398.1; AAA58398.1; CAA52200.1; BAB93458.1; AAP35784.1; BAF83814.1; EAW95727.1; AAH08062.1 

Protein Name

 Transcription factor BTF3 

Protein Synonyms/Alias

 RNA polymerase B transcription factor 3 

Gene Name

 BTF3 

Gene Synonyms/Alias

 NACB; OK/SW-cl.8 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
13	MNQEKLAKLQAQVRI	ubiquitination	[1]
49	KKLQFSLKKLGVNNI	ubiquitination	[1]
50	KLQFSLKKLGVNNIS	ubiquitination	[1]
127	RLAEALPKQSVDGKA	ubiquitination	[1]
133	PKQSVDGKAPLATGE	ubiquitination	[1]

Reference

 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 

Functional Description

 General transcription factor. BTF3 can form a stable complex with RNA polymerase II. Required for the initiation of transcription. 

Sequence Annotation

 DOMAIN 82 147 NAC-A/B.
 MOD_RES 30 30 Phosphoserine.  

Keyword

 3D-structure; Alternative splicing; Complete proteome; Nucleus; Phosphoprotein; Reference proteome; Transcription; Transcription regulation. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 206 AA 

Protein Sequence

Gene Ontology

 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0001701; P:in utero embryonic development; IEA:Compara.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc. 

Interpro

 IPR002715; Nas_poly-pep-assoc_cplx_dom. 

Pfam

 PF01849; NAC 

SMART

  

PROSITE

 PS51151; NAC_AB 

PRINTS