CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025074
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Arf-GAP domain and FG repeat-containing protein 2 
Protein Synonyms/Alias
  
Gene Name
 Agfg2 
Gene Synonyms/Alias
 Hrbl 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
132SRDPQKVKEFLQEKYubiquitination[1]
152YVPPEQVKGPSYSKGubiquitination[1]
158VKGPSYSKGSVSATPubiquitination[1]
174QGSVPEGKPIRTLLGacetylation[2]
174QGSVPEGKPIRTLLGubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Reference proteome; Zinc. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 406 AA 
Protein Sequence
MVMAAKKGPG PGGGVGGSKA EAEAASEVWC RRVRELGGCS QAGNRHCFEC AQRGVTYVDI 60
TVGSFVCTTC SGLLRGLNPP HRVKSISMTT FTEPEVLFLQ SRGNEVCRKI WLGLFDARTS 120
LIPDSRDPQK VKEFLQEKYE KKRWYVPPEQ VKGPSYSKGS VSATPVQGSV PEGKPIRTLL 180
GDPVPSLSDP ASTSSQPGSQ SQARSSSQAR SSQPPSHSST KKASTDLLAD IGGDPFAAPQ 240
VVPAFASFPG FGGQTPAHGG FANFDAFSSS PSSSTFGSLP PSVQAPFQAQ PTPAANRMLT 300
GSYSFGSGQM SAFGVAPLAA ASQPNNLADV GGLLGPRMAA GGLPGSVFGM PSQVPALQSA 360
VPGVSGSGGL PFGAYTNPFA TPAQAQLPST NPFQPNGLAS GPGFGM 406 
Gene Ontology
 GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. 
Interpro
 IPR001164; ArfGAP. 
Pfam
 PF01412; ArfGap 
SMART
 SM00105; ArfGap 
PROSITE
 PS50115; ARFGAP 
PRINTS
 PR00405; REVINTRACTNG.