| Tag | Content |
|---|
| CPLM ID | CPLM-024421 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Glucosamine-6-phosphate isomerase 1 |
Protein Synonyms/Alias | Glucosamine-6-phosphate deaminase 1; GNPDA 1; GlcN6P deaminase 1; Oscillin |
Gene Name | GNPDA1 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Bos taurus (Bovine) |
NCBI Taxa ID | 9913 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 160 | LVSRTRVKTLAMDTI | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Seems to trigger calcium oscillations in mammalian eggs. These oscillations serve as the essential trigger for egg activation and early development of the embryo (By similarity). |
Sequence Annotation | ACT_SITE 72 72 Proton acceptor; for enolization step (By
ACT_SITE 141 141 For ring-opening step (By similarity).
ACT_SITE 143 143 Proton acceptor; for ring-opening step
ACT_SITE 148 148 For ring-opening step (By similarity).
MOD_RES 64 64 N6-acetyllysine (By similarity). |
Keyword | Acetylation; Carbohydrate metabolism; Complete proteome; Cytoplasm; Hydrolase; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 289 AA |
Protein Sequence | MKLIILDHYS QASEWAAKYI RNRIIQFNPG PDKYFTLGLP TGSTPLGCYK KLIEYYKNGD 60
LSFKYVKTFN MDEYVGLPRD HPESYHSFMW NNFFKHIDIH PENTHILDGN AADLQAECDA 120
FEEKIKAAGG IELFVGGIGP DGHIAFNEPG SSLVSRTRVK TLAMDTILAN ARFFDGDLAK 180
VPTMALTVGV GTVMDAREVM ILITGAHKAF ALYKAIEEGV NHMWTVSAFQ QHPRTVFVCD 240
EDATLELKVK TVKYFKGLML VHNKLVDPLY SIKEKEIEKS QSSKKPYSD 289 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0004342; F:glucosamine-6-phosphate deaminase activity; IEA:EC. GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW. GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW. GO:0006091; P:generation of precursor metabolites and energy; IEA:Compara. GO:0006043; P:glucosamine catabolic process; IEA:Compara. GO:0006044; P:N-acetylglucosamine metabolic process; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |