CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024583
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Vacuolar protein sorting-associated protein 35C 
Protein Synonyms/Alias
 Vesicle protein sorting 35C 
Gene Name
 VPS35C 
Gene Synonyms/Alias
 At3g51310; F24M12.350 
Created Date
 July 27, 2013 
Organism
 Arabidopsis thaliana (Mouse-ear cress) 
NCBI Taxa ID
 3702 
Lysine Modification
Position
Peptide
Type
References
8MIADDDEKWLAAAIAacetylation[1]
Reference
 [1] Proteins of diverse function and subcellular location are lysine acetylated in Arabidopsis.
 Finkemeier I, Laxa M, Miguet L, Howden AJ, Sweetlove LJ.
 Plant Physiol. 2011 Apr;155(4):1779-90. [PMID: 21311031
Functional Description
 Plays a role in vesicular protein sorting. Component of the membrane-associated retromer complex which is essential in endosome-to-Golgi retrograde transport. Also involved in the efficient sorting of seed storage proteins (By similarity). The VPS29-VPS26-VPS35 subcomplex may be involved in recycling of specific cargos from endosome to the plasma membrane. 
Sequence Annotation
  
Keyword
 Complete proteome; Cytoplasm; Endosome; Golgi apparatus; Membrane; Protein transport; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 790 AA 
Protein Sequence
MIADDDEKWL AAAIAAVKQN AFYMQRAIDS NNLKDALKFS AQMLSELRTS KLSPHKYYEL 60
YMRVFNELGT LEIFFKEETG RGCSIAELYE LVQHAGNILP RLYLLCTIGS VYIKSKDVTA 120
TDILKDLVEM CRAVQHPLRG LFLRSYLAQV TRDKLPSIGS DLEGDGDAHM NALEFVLQNF 180
TEMNKLWVRM QHQGPSREKE KREKERNELR DLVGKNLHVL SQLEGVDLGI YRDTVLPRIL 240
EQVVNCKDEL AQCYLMDCII QVFPDDFHLQ TLDVLLGACP QLQPSVDIKT VLSGLMERLS 300
NYAASSVEAL PNFLQVEAFS KLNYAIGKVV EAQADLPAAA SVTLYLFLLK FTLHVYSDRL 360
DYVDQVLGSC VTQLSATGKL CDDKAAKQIV AFLSAPLEKY NNVVTILKLT NYPLVMEYLD 420
RETNKAMAII LVQSVFKNNT HIATADEVDA LFELAKGLMK DFDGTIDDEI DEEDFQEEQN 480
LVARLVNKLY IDDPEEMSKI IFTVRKHIVA GGPKRLPLTI PPLVFSALKL IRRLRGGDEN 540
PFGDDASATP KRILQLLSET VEVLSDVSAP DLALRLYLQC AQAANNCELE TVAYEFFTKA 600
YLLYEEEISD SKAQVTALRL IIGTLQRMRV FNVENRDTLT HKATGYSARL LRKPDQCRAV 660
YECAHLFWAD ECENLKDGER VVLCLKRAQR IADAVQQMAN ASRGTSSTGS VSLYVELLNK 720
YLYFLEKGNQ QVTGDTIKSL AELIKSETKK VESGAEPFIN STLRYIEFQR QQEDGGMNEK 780
YEKIKMEWFE 790 
Gene Ontology
 GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
 GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
 GO:0005771; C:multivesicular body; IDA:TAIR.
 GO:0030904; C:retromer complex; IDA:TAIR.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW. 
Interpro
 IPR005378; VPS35. 
Pfam
 PF03635; Vps35 
SMART
  
PROSITE
  
PRINTS