UniProt Accession

 B4DQ48_HUMAN; B4DQ48 

Genbank Protein ID

 AC008649; AK298635 

Genbank Nucleotide ID

 BAG60810.1 

Protein Name

 Eukaryotic translation initiation factor 3 subunit K 

Protein Synonyms/Alias

 cDNA FLJ55131, highly similar to Eukaryotic translation initiation factor 3 subunit 12 

Gene Name

 EIF3K 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
53	GFEDSVRKFICHVVG	ubiquitination	[1]
110	CSQEESIKPKNIVEK	ubiquitination	[2]
112	QEESIKPKNIVEKID	ubiquitination	[3]

Reference

 [1] Proteome-wide identification of ubiquitylation sites by conjugation of engineered lysine-less ubiquitin.
 Oshikawa K, Matsumoto M, Oyamada K, Nakayama KI.
 J Proteome Res. 2012 Feb 3;11(2):796-807. [PMID: 22053931]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Initiation factor; Protein biosynthesis; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 124 AA 

Protein Sequence

Gene Ontology

 GO:0005852; C:eukaryotic translation initiation factor 3 complex; IEA:InterPro.
 GO:0043022; F:ribosome binding; IEA:InterPro.
 GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
 GO:0006446; P:regulation of translational initiation; IEA:InterPro. 

Interpro

 IPR016024; ARM-type_fold.
 IPR009374; eIF3k.
 IPR016020; Transl_init_fac_sub12_N_euk.
 IPR011991; WHTH_DNA-bd_dom. 

Pfam

  

SMART

  

PROSITE

  

PRINTS